bis(7H-purin-6-amine); sulfuric acid

• ChemBase编号: 73227
• 分子式: C10H12N10O4S
• 平均质量: 368.33188
• 单一同位素质量: 368.07636991
• SMILES: c12c(c(ncn1)N)[nH]cn2.c12c(c(ncn1)N)[nH]cn2.S(=O)(=O)(O)O
• Canonical SMILES: OS(=O)(=O)O.Nc1ncnc2c1[nH]cn2.Nc1ncnc2c1[nH]cn2
• InChI: InChI=1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)
• InChIKey: LQXHSCOPYJCOMD-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: bis(7H-purin-6-amine); sulfuric acid; bis(9H-purin-6-amine); sulfuric acid
• IUPAC传统名: sulfuric acid; bis(vitamin B4); bis(adenine); sulfuric acid
• 别名: 腺嘌呤硫酸盐; 腺嘌呤 半硫酸盐; 6-氨基嘌呤 半硫酸盐; 腺碱 硫酸盐; 腺嘌呤 半硫酸盐; 硫酸腺嘌呤; Adenine hemisulfate; 6-Aminopurine sulfate; Adenine hemisulfate salt; 6-Aminopurine hemisulfate salt; Adenine hemisulfate salt; Adenine sulfate salt; Adenine sulfate; Adenine sulfate; 6-AMINOPURINE SULFATE

登记号

• CAS号: 321-30-2
• EC号: 206-286-5
• MDL号: MFCD00213655
• Beilstein号: 3820263
• 默克索引号: 14152
• PubChem SID: 24890667; 24890722; 162038147; 24891230
• PubChem CID: 9449

理论计算性质

• Acid pKa: 9.903183
• 质子受体: 4
• 质子供体: 2
• LogD (pH = 5.5): -0.70830727
• LogD (pH = 7.4): -0.53768605
• Log P: -0.5310127
• 摩尔折射率: 36.5993 cm^3
• 极化性: 13.358205 Å^3
• 极化表面积: 80.48 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 0.5 M HCl: soluble10 mg/mL
• 外观: powder
• 熔点: 260°C; ca 210°C dec.

安全信息

• 保存条件: -20°C
• RTECS编号: AU7140000
• 欧盟危险性物质标志: X
• 德国WGK号: 3
• 危险公开号: 22
• 安全公开号: 36
• TSCA收录: 是
• GHS危险品标识: GHS07
• GHS危险声明: H302
• GHS警示性声明: P280H
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

药理学性质

• 作用靶点: Antimetabolites

产品相关信息

• 纯度: ≥98.0% (HPLC); ≥99%; 97%; 98+%
• 级别: purum
• 成盐信息: sulfate
• 适用性: plant cell culture tested; suitable for cell culture
• 线性分子式: C5H5N5 · 1/2H2SO4

详细说明

MP Biomedicals - 05204558

MP Biomedicals Rare Chemical collection

Selleck Chemicals - S1982

Research Area: Cancer
Biological Activity:
Adenine sulfate is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA. The shape of adenine is complementary to either thymine in DNA or uracil in RNA. Adenine is one of the two purine nucleobases (the other being guanine) used in forming nucleotides of the nucleic acids. In DNA, adenine binds to thymine via two hydrogen bonds to assist in stabilizing the nucleic acid structures. In RNA, which is used for protein synthesis, adenine binds to uracil. Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose. Adenine forms adenosine triphosphate (ATP), a nucleotide, when three phosphate groups are added to adenosine. Adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between chemical reactions. [1]References on Adenine sulfate[1] http://en.wikipedia.org/wiki/Adenine, ,

Sigma Aldrich - A9126

包装
1 kg in poly bottle
25, 100 g in poly bottle
Application
Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP).

Sigma Aldrich - A2545

Application
Adenine may be used as a plant cell culture additive. Adenine Sulphate (25mg/L) in the culture media such as Murashige & Skoog media improves the frequency of multiple shoot production and recovered the chlorotic symptoms of the leaves.

参考文献

• http://en.wikipedia.org/wiki/Adenine