N-(furan-2-ylmethyl)-7H-purin-6-amine

• ChemBase编号: 72954
• 分子式: C10H9N5O
• 平均质量: 215.21136
• 单一同位素质量: 215.08070993
• SMILES: c12c(c(ncn1)NCc1occc1)[nH]cn2
• Canonical SMILES: c1coc(c1)CNc1ncnc2c1[nH]cn2
• InChI: InChI=1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)
• InChIKey: QANMHLXAZMSUEX-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: N-(furan-2-ylmethyl)-7H-purin-6-amine; N-(furan-2-ylmethyl)-9H-purin-6-amine
• IUPAC传统名: 6 furfurylaminopurine; N6-furfuryladenine
• 别名: 激动素; 6-糠氨基嘌呤; N6-呋喃甲基腺嘌呤; 激动素 溶液; 呋喃甲基腺嘌呤; Kinetin hydrochloride; 6-Furfuryladenine; N6-Furfuryladenine; 6-Furfurylaminopurine; Cytokinin; Kinetin; Kinetin; 6-[(Fur-2-ylmethyl)amino]purine; 6-CHLOROPURINE; N^6-Furfuryladenine; N-(2-Furanylmethyl)-9H-purin-6-amine; 6-(Furfurylamino)purine; FAP; KT; Kinetin (plant hormone); N-Furfuryladenine; N6-(Furfurylamino)purine; NSC 23119; 6-Chloro-9H-purine; NSC 744; Kinetin; Kinetin solution; N(6)-Furfuryladenine

登记号

• CAS号: 87-42-3; 525-79-1; 177966-68-6
• EC号: 208-382-2; 201-745-6
• MDL号: MFCD00075757
• Beilstein号: 21703
• 默克索引号: 145311
• PubChem SID: 24896228; 24871751; 24896197; 24896214; 162037874; 24896230
• PubChem CID: 3830

理论计算性质

• Acid pKa: 9.866506
• 质子受体: 4
• 质子供体: 2
• LogD (pH = 5.5): 0.42497414
• LogD (pH = 7.4): 0.55013347
• Log P: 0.5554111
• 摩尔折射率: 59.0962 cm^3
• 极化性: 21.65847 Å^3
• 极化表面积: 79.63 Å^2
• 可自由旋转的化学键: 3
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: Dichloromethane; DMF; DMSO; H2O: soluble; Water
• 外观: off-white amorphous powder; white crystalline; White Solid; Yellow Solid
• 熔点: >300°C; 264-266°C (dec.); 264-270 °C (dec.)(lit.); 265-267°C (dec.); 269-271 °C (dec.); 269-271°C; ca 270°C dec.

安全信息

• 保存条件: 0°C; -20°C; -20°C Freezer; 2-8°C, Store Under Nitrogen, Protect from light
• 保存注意事项: Irritant
• RTECS编号: AU6270000; UO7520000
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 德国WGK号: 3
• 危险公开号: R:22
• 安全公开号: 23-24/25; S:36/37/39
• TSCA收录: 是
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C

产品相关信息

• 纯度: ≥99%; >95%; ≥98% (TLC and HPLC); ≥99.0% (HPLC); 98%; 99%
• 浓度: 1 mg/mL
• 成盐信息: Free Base
• 适用性: plant cell culture tested
• 燃烧残渣: ≤0.05%
• 无菌消毒: sterile-filtered
• 产品质量级别: GMP
• Empirical Formula (Hill Notation): C10H9N5O
• 分类: Rare Derivatives of Natural Compounds

详细说明

MP Biomedicals - 02101369

Crystalline
Purity: ~99+%
We only offer this product as white crystals. Some dealers offer an off-white or yellow product. We have found that even the white crystals of other dealers do not equal our 99+% purity.

MP Biomedicals - 02102117

White crystals
Purity: >95%
Plant growth accelerator.

Selleck Chemicals - S2316

Research Area: Metabolic Disease
Biological Activity:
Kinetin(6-Furfuryladenine) is a kind of cytokinin, a class of plant hormone that promotes cell division. Kinetin is often used in plant tissue culture for inducing formation of callus (in conjunction with auxin) and to regenerate shoot tissues from callus. At present, kinetin is one of the widely used components in numerous skin care cosmetics and cosmeceuticals, such as Valeant products kinerase. [1]

Sigma Aldrich - K3253

Application
Kinetin is an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), Indole-3-butyric acid (IBA), 1-napthaleneacetic acid (NAA) or others to induce the fomation of callus and to regenerate plant tissues from callus.

Sigma Aldrich - K1885

Application
Kinetin is an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), indole-3-butyric acid (IBA), 1-napthaleneacetic acid (NAA) or others to induce the fomation of callus and to regenerate plant tissues from callus.

Sigma Aldrich - 48130

Other Notes
Plant growth regulator3,4
Biochem/physiol Actions
Kinetin has been studied as a treatment for many human disease states caused by pre-mRNA splicing errors, including familial dysautonomia1 and neurofibromatosis.2

Sigma Aldrich - K0753

Application
Kinetin is an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), indole-3-butyric acid (IBA), 1-napthaleneacetic acid (NAA) or others to induce the fomation of callus and to regenerate plant tissues from callus.

Sigma Aldrich - K3378

包装
1 g in poly bottle
5, 25 g in glass bottle
Application
Kinetin is an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), Indole-3-butyric acid (IBA), 1-napthaleneacetic acid (NAA) or others to induce the fomation of callus and to regenerate plant tissues from callus.

Toronto Research Chemicals - C379850

Shows antitumor activity against animal and human neoplasms

Toronto Research Chemicals - K570005

A cell division factor found in various plant parts and in yeast. A plant growth regulator. Augments growth of microbial cultures.

参考文献

• http://en.wikipedia.org/wiki/Kinetin
• Fry, D.W., et al.: Science, 265, 1093 (1994)
• Vesely, J., et al.: Eur. J. Biochem., 224, 771 (1994)
• Trelles, J., et al.: Biotechnol. Lett., 27, 759 (2005)
• Goudela, S., et al.: Mol. Membran. Biol., 23, 291 (2005)
• Goudela, S., et al.: Fung. Genet. Biol., 45, 459 (2005)
• Enhances the rate of cell-division in plants: Plant Physiol., 54, 644 (1974).