(1S,2S,10S,13R,14S,17S,18S)-2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5-dien-17-ol

• ChemBase编号: 72803
• 分子式: C21H32N2O
• 平均质量: 328.49158
• 单一同位素质量: 328.25146365
• SMILES: c12c(C[C@H]3[C@](C1)([C@@H]1[C@@H](CC3)[C@H]3[C@](CC1)([C@](CC3)(O)C)C)C)[nH]nc2
• Canonical SMILES: C[C@]12Cc3cn[nH]c3C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(C)O)C
• InChI: InChI=1S/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1
• InChIKey: LKAJKIOFIWVMDJ-IYRCEVNGSA-N

名称和登记号

名称

• IUPAC标准名: (1S,2S,10S,13R,14S,17S,18S)-2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^2,^1^0.0^4,^8.0^1^4,^1^8]icosa-4(8),5-dien-17-ol; (1S,2S,10S,13R,14S,17S,18S)-2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^2,^1^0.0^4,^8.0^1^4,^1^8]icosa-4,7-dien-17-ol; (1S,2S,10S,13R,14S,17S,18S)-2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5-dien-17-ol
• IUPAC传统名: stanozolol
• 别名: 17β-羟基-17α-甲基-5α-雄甾烷基[3,2-c]吡唑; 5α-雄烷-17α-甲基-17β-醇-[3,2-c]吡唑; 吡唑甲氢龙; 康力龙; 司坦唑醇; Stanozolol; Winstrol; Winstrol Depot; Stanozolol; (5α,17β)-17-Methyl-2'H-androst-2-eno[3,2-c]pyrazol-17-ol; 17-Methyl-5α-androstano[3,2-c]pyrazol-17β-ol; Anabol; Androstanazol; Androstanazole; Androstanazolestanazol; Estazol; NSC 233046; Stanazolol; Strombaject; Tevabolin; Win 14833; Winstroid

登记号

• CAS号: 10418-03-8
• EC号: 233-894-8
• MDL号: MFCD00133084
• PubChem SID: 162037724; 24899733
• PubChem CID: 25249
• ATC码: A14AA02
• CHEMBL: 1200324
• Chemspider ID: 23582
• DrugBank ID: DB06718
• KEGG ID: D00444
• 美国药典/FDA物质标识码: 4R1VB9P8V3
• 维基百科标题: Stanozolol

理论计算性质

• Acid pKa: 15.504109
• 质子受体: 2
• 质子供体: 2
• LogD (pH = 5.5): 3.6970553
• LogD (pH = 7.4): 3.6974132
• Log P: 3.6974177
• 摩尔折射率: 97.253 cm^3
• 极化性: 37.832325 Å^3
• 极化表面积: 48.91 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: Chloroform; Methanol
• 外观: White Solid; white to light yellow powder
• 熔点: 214-216°C

安全信息

• 保存条件: -20°C; Controlled Substance, -20°C Freezer
• RTECS编号: BV8741000
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 德国WGK号: 3
• 危险公开号: 63
• 安全公开号: 53-22-36/37/39
• GHS危险品标识: GHS08
• GHS警示词: Warning
• GHS危险声明: H361
• GHS警示性声明: P281
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• 毒品管制信息: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• 保存温度: 2-8°C

药理学性质

• 给药途径: Oral, Intramuscular
• 排泄: Renal: 84%
• 半衰期: 1 day
• 代谢: Hepatic
• 法定药品分级: Prescription only ; (US)
• 妊娠期药物分类: X

产品相关信息

• 级别: analytical standard, for drug analysis
• 成盐信息: Free Base

详细说明

Selleck Chemicals - S1788

Related research area: Endocrinology

Toronto Research Chemicals - S684500

Anabolic steroid. Androgen.Controlled substance.

参考文献

• http://en.wikipedia.org/wiki/Stanozolol
• Gradeen, C., et al.: J. Anal. Toxicol., 14, 120 (1990)
• Schanzer, W., et al.: J. Steroid Biochem., 36, 153 (1990)
• Yamada, M., et al.: J. Pharm. Biomed. Anal., 45, 125 (1990)