tetradecanoic acid

• ChemBase编号: 5856
• 分子式: C14H28O2
• 平均质量: 228.37092
• 单一同位素质量: 228.20893014
• SMILES: C(=O)(O)CCCCCCCCCCCCC
• Canonical SMILES: CCCCCCCCCCCCCC(=O)O
• InChI: InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
• InChIKey: TUNFSRHWOTWDNC-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: tetradecanoic acid
• IUPAC传统名: myristic acid
• 别名: 十四烷酸; 肉豆蔻酸; 十四烷酸; MYRISTIC ACID; C14:0 (Lipid numbers); 1-Tridecanecarboxylic acid; C14:0; NSC 5028; Myristic acid; Tetradecanoic acid; Myristic acid; Tetradecanoic acid; tetradecanoic acid

登记号

• CAS号: 544-63-8
• EC号: 208-875-2
• MDL号: MFCD00002744
• Beilstein号: 508624
• 默克索引号: 146333
• PubChem SID: 99444702; 24886049; 24886048; 160969283; 24901314; 24901313; 24896795
• PubChem CID: 11005
• CHEMBL: 111077
• Chemspider ID: 10539
• FEMA编号: 2764
• 维基百科标题: Myristic_acid
• 欧洲委员会编号: 16
• Flavis Number: 8.016

理论计算性质

JChem

• Acid pKa: 4.9520197
• 质子受体: 2
• 质子供体: 1
• LogD (pH = 5.5): 4.71164
• LogD (pH = 7.4): 2.9525049
• Log P: 5.3674455
• 摩尔折射率: 67.8816 cm^3
• 极化性: 27.025951 Å^3
• 极化表面积: 37.3 Å^2
• 可自由旋转的化学键: 12
• 里宾斯基五规则: false

ALOGPS 2.1

• Log P: 6.1
• LOG S: -5.12
• 溶解度: 1.72e-03 g/l

分子性质

理化性质

• 熔点: 52-54 °C(lit.); 53-56 °C; 53-56°C; 54.4 °C; 54.5 °C; 54.5°C
• 沸点: 250 °C/100 mmHg(lit.); 250.5 °C at 100 mmHg; 326°C; 326°C; ca. 326 °C at 1013 hPa
• 闪点: >113 °C; >235.4 °F; 175°C(347°F); ca. 175 °C (Cleveland Open Cup)
• 密度: 0.862; 0.8622 g/cm^3; ca. 858 kg/m3 at 60 °C
• 蒸汽压: .0065 hPa at 20 °C
• 疏水性(logP): 6.154
• 感官: oily; waxy

安全信息

• 保存条件: 0°C
• RTECS编号: QH4375000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: nwg
• 危险公开号: 36/37/38; 38; R:36/37/38
• 安全公开号: 26-37; S:20-25-26-37/39
• TSCA收录: 是
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315; H315-H319-H335; H319
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A; P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 保存温度: -20°C
• Regulation Compliance: EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR (172.210); FDA 21 CFR (172.860); FDA 21 CFR (173.340)

药理学性质

• 过敏源: no known allergens

产品相关信息

• 纯度: ~95%; ≥98.0% (GC); ≥98.5% (GC); ≥99%; ≥99.5%; ≥99.5% (GC); 95%; 95+%; 98%; 99-100%
• 级别: analytical standard; certified reference material; FG; Halal; Kosher; natural; NI; Sigma Grade; TECHNICAL
• 包装: pkg of 1 g
• 有效期: (limited shelf life, expiry date on the label)
• Pharmacopeia Traceability: traceable to USP 1448990
• 线性分子式: CH3(CH2)12COOH

详细说明

MP Biomedicals - 02102375

Technical Grade
Purity: ~95%
Crystalline

MP Biomedicals - 02100870

Crystalline
Purity: 99-100%

MP Biomedicals - 05216758

MP Biomedicals Rare Chemical collection

DrugBank - DB08231

Drug information: experimental

Sigma Aldrich - 153796

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - PHR1124

General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Other Notes
Values of analytes vary lot to lot.
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - W276405

包装
1 kg in poly bottle
5, 10 kg in poly drum
1 sample in glass bottle
100 g in poly bottle
25 kg in fiber drum
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 130087

包装
1 kg in poly bottle
5 g in glass bottle
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70079

Other Notes
结合到血清白蛋白2
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - M3128

Biochem/physiol Actions
Myristic acid is a straight-chain 14-carbon fatty acid. Diets rich in myristic acid, along with lauric and palmitic acids, are associated with increased serum levels of low densisity lipoprotein cholesterol.
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.
包装
10, 100, 500 g in poly bottle

Sigma Aldrich - W276413

包装
1 kg in poly bottle
1 sample in glass bottle
5, 10, 25 kg in fiber drum
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70080

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70082

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.