(methanesulfonylsulfanyl)methane

• ChemBase编号: 53161
• 分子式: C2H6O2S2
• 平均质量: 126.19784
• 单一同位素质量: 125.98092143
• SMILES: CS(=O)(=O)SC
• Canonical SMILES: CSS(=O)(=O)C
• InChI: InChI=1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3
• InChIKey: XYONNSVDNIRXKZ-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: (methanesulfonylsulfanyl)methane
• IUPAC传统名: methyl methanethiosulfonate
• 别名: S-甲基硫代甲基砜; 甲基硫代磺酸甲酯; S-Methyl methanesulfonothioate; S-Methyl methanethiosulfonate; Methanesulfonothioic Acid S-Methyl Ester; Thiomethanesulfonic Acid S-Methyl Ester; NSC 21545; S-Methyl Methanesulfonothioate; S-Methyl Methanethio-sulfonate; Methyl Methanethiosulfonate; S-Methyl thiomethanesulfonate; MMTS; METHYL METHANETHIO-SULFONATE

登记号

• CAS号: 2949-92-0
• EC号: 220-970-0
• MDL号: MFCD00007565
• Beilstein号: 1446059
• PubChem SID: 24852530; 162057924; 24883247
• PubChem CID: 18064

理论计算性质

• 质子受体: 2
• 质子供体: 0
• LogD (pH = 5.5): -0.061644528
• LogD (pH = 7.4): -0.061644528
• Log P: -0.061644528
• 摩尔折射率: 27.5405 cm^3
• 极化性: 11.784489 Å^3
• 极化表面积: 34.14 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: c =1.23g/ml; DMSO
• 外观: Light Yellow Liquid
• 沸点: 69-71 °C/0.4 mmHg(lit.); 69-71°C/0.4mm
• 闪点: 188.6 °F; 87 °C
• 密度: 1.29 g/ml; 1.337 g/mL at 20 °C; 1.337 g/mL at 25 °C(lit.)
• 折射率: n20/D 1.513; n20/D 1.513(lit.)

安全信息

• 保存条件: -20°C Freezer, Under Inert Atmosphere; Room Temperature (15-30°C)
• 保存注意事项: IRRITANT; Water Sensitive
• RTECS编号: PB2765000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 2
• 危险公开号: 36
• 安全公开号: 26
• TSCA收录: false
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H319
• GHS警示性声明: P305 + P351 + P338
• 个人保护装置: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• 保存温度: 2-8°C

产品相关信息

• 纯度: ≥98.0% (GC); 97%; 99%
• 级别: purum
• 线性分子式: CH3SO2SCH3

详细说明

MP Biomedicals - 02151663

Brown liquid
1 ml = approx. 1.29 g
Reagent for rapid, selective modification of sulfhydryl groups of enzymes.

Sigma Aldrich - 208795

包装
1, 10 g in glass bottle
Application
亚磺酰化试剂，用于 β-酮亚砜、1亚甲基化合物、2丙二酸半酯3以及芳基格氏试剂。4

Sigma Aldrich - 64306

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Caution
储存时可能变为黄色
Other Notes
很多应用中的甲基亚磺酰化试剂1；用于环酮的 α-甲基亚磺酰化反应2；由硫醇制得甲基二硫化物；酶的选择性可逆失活3,4

Toronto Research Chemicals - M321500

Used for the rapid and selective modification of sulfhydryl groups of enzymes. Useful for mapping the pore-lining regions of the ryanodine receptor.

参考文献

• Smith, D.J., et al., Biochemistry, 14: 766 (1975).
• Stauffer, D.A., and Karlin, A.: Biochemistry, 33, 6840 (1994)
• Yang, N. et al.: Neuron, 16, 113 (1994)
• Kuner, T. et al.: Neuron, 17, 343 (1994)
• Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1994)
• Dunten, R.L., et al.: Biochemistry, 32, 3139-3145