potassium iodide

• ChemBase编号: 4452
• 分子式: IK
• 平均质量: 166.00277
• 单一同位素质量: 165.86817968
• SMILES: [K+].[I-]
• Canonical SMILES: [K+].[I-]
• InChI: InChI=1S/HI.K/h1H;/q;+1/p-1
• InChIKey: NLKNQRATVPKPDG-UHFFFAOYSA-M

名称和登记号

名称

• IUPAC标准名: potassium iodide
• IUPAC传统名: potassium ion iodide; potassium iodide
• 商标名: ThyroShield
• 别名: 碘化钾, 超干; 碘化钾, Puratronic®; 碘化钾 溶液; 碘化钾; 碘化钾; 碘化钾, ACS; Potassium iodide, ultra dry; Potassium iodide, Puratronic®; Potassium Iodide; Potassium iodide solution; Kalii iodidum; Potassium iodide; POTASSIUM IODIDE, ACS; Potassium iodide solution; Potassium iodide concentrate; Potassium iodide, ACS

登记号

• CAS号: 7681-11-0
• EC号: 213-659-4; 231-791-2; 231-659-4
• MDL号: MFCD00011405
• 默克索引号: 147643
• PubChem SID: 24845426; 24858301; 24852483; 24861659; 24881868; 24863788; 24860730; 24881869; 24852091; 99443267; 24866859; 24898376; 24898914; 24853302; 24861761; 160967884
• PubChem CID: 4875
• CHEBI ID: 8346
• ATC码: R05CA02; S01XA04; V03AB21
• CHEMBL: 1141
• Chemspider ID: 4709
• DrugBank ID: DB06715
• KEGG ID: D01016
• 美国药典/FDA物质标识码: 1C4QK22F9J
• 维基百科标题: Potassium_iodide

理论计算性质

• Acid pKa: 3.09
• 质子受体: 0
• 质子供体: 0
• LogD (pH = 5.5): 0.2
• LogD (pH = 7.4): 0.2
• Log P: 0.2
• 摩尔折射率: 0.0 cm^3
• 极化性: 2.6527095 Å^3
• 极化表面积: 0.0 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 128 g/100 ml (0 °C) ; 140 g/100 mL (20 °C) ; 176 g/100 mL (60°C) ; 206 g/100 mL (100°C) in water; 2 g/100 mL (ethanol) ; soluble in acetone (1.31 g/100 mL) ; slightly soluble in ether, ammonia; H2O: soluble1 M at 20 °C, clear, colorless; Soluble in water, alcohol, acetone, and glycerol
• 外观: -10 Mesh Beads, Ampouled under argon; beads; Crystalline; crystals and lumps; Granular; Powder; white crystalline solid
• 熔点: 681 °C(lit.); 681°C; 681°C
• 沸点: 1330°C; 1330°C
• 密度: 3.12; 3.123 g/cm^3
• 折射率: 1.677
• 蒸汽压: 1 mmHg ( 745 °C)
• pH值: 6.0-9.0 (20 °C, 5%); 6.0-9.0 (25 °C, 1 M in H2O); 6.0-9.2 (25 °C, 5%); 6.0-9.2 (25 °C, 50 mg/mL in H2O)

安全信息

• 保存条件: -20°C; Room Temperature (15-30°C), Desiccate, Protect from light
• 保存注意事项: Hygroscopic
• RTECS编号: TT2975000
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C); 有害性(Harmful) (Xn)
• 德国WGK号: 1; nwg
• 危险公开号: 22-34; 22-36/38; R:22
• 安全公开号: 26; 26-36/37/39-45; S:36/37/39
• TSCA收录: 是
• 欧盟危险品索引: Not listed
• GHS危险品标识: GHS05; GHS07
• GHS警示词: Danger; Warning
• NFPA704:
  

  0

  1

  0
• GHS危险声明: H302-H315-H319; H314
• GHS警示性声明: P280-P305 + P351 + P338-P310; P305 + P351 + P338
• 个人保护装置: Eyeshields, Gloves; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US); Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品相关信息

• 纯度: ≥99.0%; ≥99.0% (AT); ≥99.5%; ≥99.5% (AT); ≥99.99% trace metals basis; ≥99.999% (metals basis); 98%; 99%; 99.0% min; 99.0-100.5% (calc. to the dried substance); 99.9% (metals basis); 99.99% (metals basis); 99.995% (metals basis); 99.998% (metals basis); 99.998% trace metals basis
• 浓度: 0.1 M; 0.1 M KI; 1 M KI; 15 % (w/v); 3 M KI
• 级别: ACS; ACS reagent; anhydrous; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; REAGENT; ReagentPlus®; SAJ first grade; TraceSELECT®
• 成盐信息: inorganic salt
• 颗粒大小: -10 mesh
• 包装: pkg of 0.1 mol (16.601 g KI)
• 适用性: complies for appearance of solution; meets EP, BP, USP testing specifications; meets USP testing specifications; plant cell culture tested; suitable for oxidant determination
• 杂质: <100 ppm water; ≤0.0005% heavy metals (as Pb); ≤0.0005% P; ≤0.001% heavy metals (as Pb); ≤0.001% N compounds; ≤0.001% total nitrogen (N); ≤0.005% Insoluble matter; ≤0.005% insolubles; ≤0.005% thiosulfate (S2O3); ≤0.01% thiosulfate (S2O3); ≤0.02% free alkali (as KOH); ≤10 mg/kg total nitrogen; ammonium, in accordance; insoluble matter, passes filter test; organic volatile impurities, complies (GC); residual solvents, in accordance
• 痕量阳离子: Al: ≤0.0005%; Al: ≤0.02 mg/kg; Al: ≤5 mg/kg; As: ≤0.01 mg/kg; As: ≤0.1 mg/kg; Ba: ≤0.002%; Ba: ≤0.5 mg/kg; Ba: ≤10 mg/kg; Ba: ≤20 mg/kg; Ba: ≤5 mg/kg; Ba:, in accordance; Bi: ≤5 mg/kg; Ca: ≤0.001%; Ca: ≤0.002%; Ca: ≤0.1 mg/kg; Ca: ≤10 mg/kg; Ca: ≤50 mg/kg; Cd: ≤0.01 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Ce: ≤0.01 mg/kg; Co: ≤0.01 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤0.01 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤0.01 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Eu: ≤0.01 mg/kg; Fe: ≤0.0005%; Fe: ≤0.05 mg/kg; Fe: ≤10 mg/kg; Fe: ≤2 mg/kg; Fe: ≤3 mg/kg; Fe: ≤3 ppm; Fe: ≤5 mg/kg; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤5 ppm; Hg: ≤0.005 mg/kg; La: ≤0.01 mg/kg; Li: ≤0.5 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤0.001%; Mg: ≤0.05 mg/kg; Mg: ≤10 mg/kg; Mg: ≤5 mg/kg; Mn: ≤0.01 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.005%; Na: ≤0.05%; Na: ≤2000 mg/kg; Na: ≤300 mg/kg; Na: ≤5 mg/kg; Na: ≤50 mg/kg; NH4+: ≤0.05%; Ni: ≤0.01 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤0.01 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sc: ≤0.01 mg/kg; Sm: ≤0.01 mg/kg; Sr: ≤0.1 mg/kg; Sr: ≤5 mg/kg; Tl: ≤0.01 mg/kg; Y: ≤0.01 mg/kg; Yb: ≤0.01 mg/kg; Zn: ≤0.0005%; Zn: ≤0.01 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg
• 痕量阴离子: bromide, chloride (as Cl-): ≤100 mg/kg; bromide, chloride (as Cl-): ≤200 mg/kg; bromide, chloride (as Cl-): ≤50 mg/kg; chloride (Cl-): ≤0.01%; chloride, bromide (as Cl)-: ≤0.01%; iodate (IO3-): ≤2 mg/kg; iodate (IO3-): ≤3 mg/kg; iodate (IO3-): ≤3 ppm; iodate (IO3-): in accordance; nitrate (NO3-): in accordance; nitrite (NO2-): in accordance; phosphate (PO43-): ≤0.001%; phosphate (PO43-): ≤10 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤10 mg/kg; sulfate (SO42-): ≤100 mg/kg; sulfate (SO42-): ≤50 mg/kg
• 有效期: (limited shelf life, expiry date on the label)
• 干燥失重: ≤0.2% loss on drying; ≤0.2% loss on drying, 105 °C; ≤0.2% loss on drying, 150 °C; ≤0.5% loss on drying, 105 °C; ≤0.5% loss on drying, 110 °C
• 品质说明: meets analytical specification of Ph. Eur. BP, USP; volumetric
• Factor: 1.000 ±0.001; 1.000 ±0.005
• 药典: testing & handling conforms to Pharmacopeia
• 产品线: BioUltra
• abs.: absorption1M/273 nm, H2O cut-off
• 线性分子式: KI

详细说明

DrugBank - DB06715

• Drug Groups: approved
• Description: Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
• Indication: Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
• Pharmacology: It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.
• External Links: Wikipedia

MP Biomedicals - 02191513

Crystalline

MP Biomedicals - 02152562

ACS Reagent Grade

Selleck Chemicals - S1897

Research Area: Endocrinology
Biological Activity:
Potassium iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine. It may be used before and after administration of medicine containing radioactive iodine or after accidental exposure to radioactive iodine. [1]

Sigma Aldrich - 60399

Other Notes
Chaotropic agent which, in high concentrations can dissolve a gel matrix1; Recovery of DNA from gel slices by gel dissolution2,3

Sigma Aldrich - 204102

包装
10, 50 g in amber poly
250 g in poly bottle

Sigma Aldrich - 429422

包装
5, 25 g in ampule

Sigma Aldrich - 35175

General description
请访问 滴定中心 了解更多信息。
包装
产品编号中的后缀 -VP 或 -VOLPAC 说明包装在 5L 或 10L VOLPAC 容器中。

Sigma Aldrich - 34275

General description
请访问 滴定中心 了解更多信息。

Sigma Aldrich - 30533

Application
与抗坏血酸一起通过氢化物发生-原子吸收光谱法进行形态分析
法律信息
TraceSELECT 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 38110

General description
concentration after dilution to 1L: 0.1mol/L; amount of substance 0.1mol (16.601 g KI)
请访问 滴定中心 了解更多信息。

Sigma Aldrich - 207969

包装
100, 500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 221945

包装
12 kg in poly drum
2.5 kg in poly bottle
5, 100, 500 g in poly bottle
50 kg in fiber drum

参考文献

• http://www.rxlist.com/phospholine-drug.htm