1-(morpholine-4-carboximidoyl)guanidine hydrochloride

• ChemBase编号: 37610
• 分子式: C6H14ClN5O
• 平均质量: 207.66126
• 单一同位素质量: 207.08868777
• SMILES: C(=N)(NC(=N)N)N1CCOCC1.Cl
• Canonical SMILES: N=C(N1CCOCC1)NC(=N)N.Cl
• InChI: InChI=1S/C6H13N5O.ClH/c7-5(8)10-6(9)11-1-3-12-4-2-11;/h1-4H2,(H5,7,8,9,10);1H
• InChIKey: FXYZDFSNBBOHTA-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 1-(morpholine-4-carboximidoyl)guanidine hydrochloride
• IUPAC传统名: virustat hydrochloride; 1-(morpholine-4-carboximidoyl)guanidine hydrochloride
• 别名: N-(2-胍基-亚胺甲基)-吗啉 盐酸盐; 吗啉胍 盐酸盐; N-[Amino(imino)methyl]morpholine-4-carboximidamide hydrochloride; Moroxydine hydrochloride; N-(Aminoiminomethyl)-4-morpholinecarboximidamide hydrochloride; Moroxydine hydrochloride

登记号

• CAS号: 3160-91-6; 3731-59-7
• EC号: 223-093-1
• MDL号: MFCD00012798
• PubChem SID: 161000917; 24856823
• PubChem CID: 76621

理论计算性质

• 质子受体: 6
• 质子供体: 4
• LogD (pH = 5.5): -5.9631705
• LogD (pH = 7.4): -5.6971397
• Log P: -1.1369298
• 摩尔折射率: 65.7172 cm^3
• 极化性: 16.682163 Å^3
• 极化表面积: 98.22 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 熔点: 211-214 °C(lit.)

安全信息

• 保存条件: -20°C
• 保存注意事项: IRRITANT
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 3
• 危险公开号: 36/37/38
• 安全公开号: 26-37/39
• TSCA收录: false
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves

产品相关信息

• 纯度: 99%
• 成盐信息: hydrochloride
• Empirical Formula (Hill Notation): C6H13N5O · HCl

详细说明

Selleck Chemicals - S2486

Research Area: Infection
Biological Activity:
Moroxydine HCl is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines. Structurally moroxydine is a heterocyclic biguanidine. [1] It possesses antiviral activity and is of value in the prevention and treatment of influenza. Although its mechanism of action is not fully known the effects seem to be due to an influence on the virus host-cell system. Oral medication has been shown to be effective against influenza, and small doses taken over a period of time have been shown to protect animals against influenza and other viral conditions. After preliminary trials with intramuscular injections the oral form of medication has been proven to be equally effective: pain usually disappears after two days, temperature reaches normal values and the lesion ceases to spread.

Sigma Aldrich - 278610

包装
1 g in glass bottle

参考文献

• http://en.wikipedia.org/wiki/Moroxydine