(3'aS,6'aR)-7-chloro-3'-(1-hydroxyethyl)-5'-(2-phenylethyl)-1,2,3',3'a,4',5',6',6'a-octahydro-2'H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'-trione

• ChemBase编号: 211780
• 分子式: C23H22ClN3O4
• 平均质量: 439.89148
• 单一同位素质量: 439.12988388
• SMILES: C12([C@H]3[C@H](C(=O)N(C3=O)CCc3ccccc3)C(N1)C(O)C)C(=O)Nc1c2cccc1Cl
• Canonical SMILES: CC(C1NC2([C@H]3[C@@H]1C(=O)N(C3=O)CCc1ccccc1)C(=O)Nc1c2cccc1Cl)O
• InChI: InChI=1S/C23H22ClN3O4/c1-12(28)18-16-17(21(30)27(20(16)29)11-10-13-6-3-2-4-7-13)23(26-18)14-8-5-9-15(24)19(14)25-22(23)31/h2-9,12,16-18,26,28H,10-11H2,1H3,(H,25,31)/t12?,16-,17-,18?,23?/m0/s1
• InChIKey: ZDZLHYCCYICKBX-VKCSONJISA-N

名称和登记号

名称

• IUPAC标准名: (3'aS,6'aR)-7-chloro-3'-(1-hydroxyethyl)-5'-(2-phenylethyl)-1,2,3',3'a,4',5',6',6'a-octahydro-2'H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'-trione
• IUPAC传统名: (3'aS,6'aR)-7-chloro-3'-(1-hydroxyethyl)-5'-(2-phenylethyl)-2',3',3'a,6'a-tetrahydro-1H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,4',6'-trione

登记号

• PubChem SID: 164267690
• PubChem CID: 16404068

理论计算性质

• Acid pKa: 11.537685
• 质子受体: 5
• 质子供体: 3
• LogD (pH = 5.5): 0.021960448
• LogD (pH = 7.4): 1.6278014
• Log P: 1.9537562
• 摩尔折射率: 115.2275 cm^3
• 极化性: 44.53557 Å^3
• 极化表面积: 98.74 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

产品相关信息

• 分类: Derivatives & analogs of Natural Compounds