6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride

• ChemBase编号: 178485
• 分子式: C11H13ClN2S
• 平均质量: 240.75232
• 单一同位素质量: 240.04879711
• SMILES: Cl.S1CCN2C1=NC(C2)c1ccccc1
• Canonical SMILES: C1CN2C(=NC(C2)c2ccccc2)S1.Cl
• InChI: InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
• InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• IUPAC传统名: tetramisole hydrochloride hydrochloride
• 别名: 2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole Hydrochloride; (+/-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Hydrochloride; (+/-)-Tetramisole Hydrochloride; Anthelvet; Citarin; Concurat; Curaminth; DL-Tetramisole Hydrochloride; Verminject; NSC 170985; NSC 215179; Tetramisole Hydrochloride

登记号

• CAS号: 5086-74-8
• PubChem SID: 164234395
• PubChem CID: 68628

理论计算性质

• 质子受体: 2
• 质子供体: 0
• LogD (pH = 5.5): 0.91581506
• LogD (pH = 7.4): 2.220205
• Log P: 2.358227
• 摩尔折射率: 60.0784 cm^3
• 极化性: 23.02744 Å^3
• 极化表面积: 15.6 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

详细说明

Toronto Research Chemicals - T305680

Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.

参考文献

• Janjatovic, A., et al.: J. Vet. Pharmacol. Ther., 31, 328 (2008)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2008)