2-amino-4-(hydroxycarbamoyl)butanoic acid

• ChemBase编号: 155236
• 分子式: C5H10N2O4
• 平均质量: 162.1439
• 单一同位素质量: 162.06405681
• SMILES: C(CC(=O)NO)C(C(=O)O)N
• Canonical SMILES: ONC(=O)CCC(C(=O)O)N
• InChI: InChI=1S/C5H10N2O4/c6-3(5(9)10)1-2-4(8)7-11/h3,11H,1-2,6H2,(H,7,8)(H,9,10)
• InChIKey: YVGZXTQJQNXIAU-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 2-amino-4-(hydroxycarbamoyl)butanoic acid
• IUPAC传统名: glutamine hydroxamate
• 别名: L-γ-Glutamylhydroxamic acid; L-5-N-Hydroxyglutamine; L-Glutamic acid γ-monohydroxamate

登记号

• CAS号: 1955-67-5
• MDL号: MFCD00057719
• PubChem SID: 162249374; 24895091
• PubChem CID: 3484

理论计算性质

• Acid pKa: 1.9268305
• 质子受体: 5
• 质子供体: 4
• LogD (pH = 5.5): -4.004595
• LogD (pH = 7.4): -4.0225725
• Log P: -4.0046434
• 摩尔折射率: 34.8745 cm^3
• 极化性: 14.025267 Å^3
• 极化表面积: 112.65 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

安全信息

• 德国WGK号: 3
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C

产品相关信息

• Empirical Formula (Hill Notation): C5H10N2O4

详细说明

Sigma Aldrich - G2253

Biochem/physiol Actions
L-Glutamic acid γ-monohydroxamate [L-Glu(gamma)HXM] is used as a vanadium ligand which potentiates vanadiums metabolic activity. L-Glu(gamma)HXM is also used as a substrate for E. coli asparagine synthetase B and as an ATP-dependent irreversible inhibitor of Escherichia coli gamma-glutamylcysteine synthetase.