(5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol

• ChemBase编号: 134419
• 分子式: C12H22O11
• 平均质量: 342.29648
• 单一同位素质量: 342.11621152
• SMILES: C(C1[C@H](C(C(C(O1)O)O)O)O[C@H]1C(C(C(C(O1)CO)O)O)O)O
• Canonical SMILES: OCC1OC(O)C(C([C@@H]1O[C@@H]1OC(CO)C(C(C1O)O)O)O)O
• InChI: InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
• InChIKey: GUBGYTABKSRVRQ-WFVLMXAXSA-N

名称和登记号

名称

• IUPAC标准名: (5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol
• IUPAC传统名: (5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol
• 别名: 纤维素, 微晶; DEAE-Sephacel®; Diethylaminoethyl–Sephacel®; DEAE-Cellulose; Express-Ion™ exchanger? D free base; Cellulose, microcrystalline; Cellulose DEAE; Diethylaminoethyl-cellulose; DEAE-Cellulose

登记号

• CAS号: 9013-34-7; 9004-34-6
• EC号: 232-674-9
• MDL号: MFCD00146622; MFCD00081512
• 默克索引号: 141965
• PubChem SID: 24894457; 24858386; 24893780; 24894027; 24893308; 24896090; 162228695
• PubChem CID: 16211032

理论计算性质

• Acid pKa: 11.2543745
• 质子受体: 11
• 质子供体: 8
• LogD (pH = 5.5): -4.703376
• LogD (pH = 7.4): -4.7034354
• Log P: -4.703375
• 摩尔折射率: 68.3367 cm^3
• 极化性: 28.969793 Å^3
• 极化表面积: 189.53 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: false

分子性质

理化性质

• 外观: aqueous ethanol suspension; fibers; preswollen, microgranular
• 闪点: 129.2 °F; 54 °C

安全信息

• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 联合国危险货物编号: 1170
• 德国WGK号: 1; 3
• 联合国危险货物等级: 3
• 联合国危险货物包装类别(PG): 3
• 危险公开号: 10; 37
• TSCA收录: 是
• GHS危险品标识: GHS02; GHS07
• GHS警示词: Warning
• GHS危险声明: H226; H335
• GHS警示性声明: P261-P304+P340-P312-P405-P403+P233-P501A
• RID/ADR: UN 1170 3/PG 3
• 保存温度: 2-8°C

产品相关信息

• 颗粒大小: 100-200 μm; 40-160 μm (wet); 60-130 μm
• 孔径尺寸: ~1,000,000 Da exclusion limit
• 杂质: ~70% water
• 其他组分: ~70% moisture content
• Binding Capacity: 100-140 μeq/mL, gel
• pH范围: 2 - 9
• 基质活性基团: DEAE (diethylaminoethyl)
• 特征: flow rate 150 cm/hr
• Capacity: ~0.3 meq/g capacity; ~0.3 meq/g(as supplied); ~1.0 meq/g small ion capacity; ~1.0 meq/g(dry); 1 meq/g

详细说明

Sigma Aldrich - D3764

Application
DEAE-Cellulose is used in ion exchange chromatography, protein chromatography and anion exchange media. DEAE cellulose has been used to study acute myocardial infarction

Sigma Aldrich - E2145

Application
Express-Ion exchangers are weakly basic anion exchangers used in protein chromatography, ion exchange chromatography, cation exchange media, cellulose ion exchange TLC adsorbents and DEAE-cellulose anion exchange TLC adsorbents.
法律信息
Express-Ion is a trademark of Whatman International Ltd.

Sigma Aldrich - D6418

Application
DEAE-Cellulose is used in ion exchange chromatography, protein chromatography and anion exchange media. DEAE cellulose has been used to study acute myocardial infarction.

Sigma Aldrich - I6505

包装
1 L in glass bottle
100, 500 mL in glass bottle
Physical form
Suspension in 20% ethanol
Application
Diethylaminoethyl Sephacel is used in protein chromatography, ion exchange chromatography and anion exchange media. Diethylaminoethyl Sephacel has been used to study sperm motility, sperm capacitation and sperm-oocyte interactions. Diethylaminoethyl Sephacel has also been used to study patients with IgA nephropathy.
法律信息
Sephacel is a registered trademark of GE Healthcare