(2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal

• ChemBase编号: 134305
• 分子式: C20H28O
• 平均质量: 284.43572
• 单一同位素质量: 284.21401552
• SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C\C=C\C(=C\C=O)\C)/C
• Canonical SMILES: O=C/C=C(/C=C/C=C(\C=C\C1=C(C)CCCC1(C)C)/C)\C
• InChI: InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8-,17-13+
• InChIKey: NCYCYZXNIZJOKI-MKOSUFFBSA-N

名称和登记号

名称

• IUPAC标准名: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
• IUPAC传统名: 9-cis-retinal
• 别名: 维生素 A 醛; 9-顺式视黄醛; 9-cis-Retinal; 9-Z-Retinal; 9-cis-Retinaldehyde; 9-cis-Vitamin A Aldehyde; Isoretinene a; 9-cis-Retinal

登记号

• CAS号: 514-85-2
• EC号: 208-188-8
• MDL号: MFCD00135842
• PubChem SID: 24899382; 162228582
• PubChem CID: 6436082

理论计算性质

• 质子受体: 1
• 质子供体: 0
• LogD (pH = 5.5): 4.8557515
• LogD (pH = 7.4): 4.8557515
• Log P: 4.8557515
• 摩尔折射率: 96.8654 cm^3
• 极化性: 35.792797 Å^3
• 极化表面积: 17.07 Å^2
• 可自由旋转的化学键: 5
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: Chloroform; Ether
• 外观: Pale-Yellow Solid
• 熔点: 56-58 °C(lit.); 61-63°C

安全信息

• 保存条件: Amber Vial, -86°C Freezer
• RTECS编号: VH6406500
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 德国WGK号: 3
• 危险公开号: 20/21/22-38
• 安全公开号: 22-36/37
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H302-H312-H315-H332
• GHS警示性声明: P280
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 保存温度: -20°C

产品相关信息

• 运输包装: dry ice

详细说明

Sigma Aldrich - R5754

Biochem/physiol Actions
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.9-cis retinal is a natural ligand (chromophore) of the vertebrate rod visual pigment. 9-cis retinal is used in studies on the mechanisms of visual function.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R5754.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Toronto Research Chemicals - R239850

9-cis-Retinal is an isomer of all-trans-Retinal (R240000).

参考文献

• Yan, E., et al.: Biochemistry, 43, 10867 (2004)
• Kukura, P., et al.: Science, 310, 1006 (2004)
• Ridge, K., et al.: J. Biol. Chem., 282, 9297 (2004)