potassium (4S)-4-amino-4-carboxybutanoate hydrate

• ChemBase编号: 134148
• 分子式: C5H10KNO5
• 平均质量: 203.2349
• 单一同位素质量: 203.01960411
• SMILES: C(CC(=O)[O-])[C@@H](C(=O)O)N.O.[K+]
• Canonical SMILES: [O-]C(=O)CC[C@@H](C(=O)O)N.O.[K+]
• InChI: InChI=1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1
• InChIKey: XIBUKSQTWSKJMQ-QTNFYWBSSA-M

名称和登记号

名称

• IUPAC标准名: potassium (4S)-4-amino-4-carboxybutanoate hydrate
• IUPAC传统名: potassium (4S)-4-amino-4-carboxybutanoate hydrate
• 别名: (S)-2-氨基戊二酸; L-2-氨基戊二酸 钾盐; L-谷氨酸钾; L-谷氨酸 钾盐 一水合物; L-谷氨酸单钾盐单水合物; L-谷氨酸 单钾盐 一水合物; L-α-Aminoglutaric acid potassium salt; Glu; L-Glutamic acid potassium salt monohydrate; Monopotassium glutamate monohydrate; Potassium L-glutamate; L-Glutamic acid monopotassium salt monohydrate

登记号

• CAS号: 6382-01-0
• MDL号: MFCD00150343
• Beilstein号: 3637377
• PubChem SID: 24895045; 24873010; 162228425; 24895063
• PubChem CID: 23695977

理论计算性质

• Acid pKa: 1.8777773
• 质子受体: 5
• 质子供体: 2
• LogD (pH = 5.5): -4.4458017
• LogD (pH = 7.4): -6.180975
• Log P: -3.241447
• 摩尔折射率: 42.1248 cm^3
• 极化性: 12.57248 Å^3
• 极化表面积: 103.45 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: white powder
• 熔点: 115-118°C
• 比旋光度: [α]20/D +23±1°, c = 5% in 5 M HCl

安全信息

• RTECS编号: MA1450000
• 德国WGK号: 2
• TSCA收录: 是
• GHS危险声明: H303
• GHS警示性声明: P312
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

药理学性质

• 相关基因信息: human ... GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)mouse ... GRIK1(14805), GRIK2(14806), GRIK3(14807), GRIK4(110637), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)rat ... GRIK1(29559), GRIK2(54257), GRIK3(298521), GRIK4(24406), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

产品相关信息

• 纯度: ≥99% (TLC); ≥99.0%; ≥99.0% (NT)
• 级别: puriss. p.a.
• 适用性: suitable for insect cell culture
• 杂质: ≤0.5% foreign amino acids
• 痕量阳离子: Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; NH4+: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• 痕量阴离子: chloride (Cl-): ≤100 mg/kg; sulfate (SO42-): ≤100 mg/kg
• 线性分子式: KOOCCH2CH2CH(NH2)COOH · H2O

详细说明

Sigma Aldrich - G1149

Biochem/physiol Actions
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Sigma Aldrich - G1501

Biochem/physiol Actions
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.