[2-hydroxy-3-(octadeca-9,12-dienoyloxy)propoxy]phosphonic acid

• ChemBase编号: 133713
• 分子式: C21H39O7P
• 平均质量: 434.503921
• 单一同位素质量: 434.24334022
• SMILES: CCCCC/C=C/C/C=C/CCCCCCCC(=O)OCC(COP(=O)(O)O)O
• Canonical SMILES: CCCCC/C=C/C/C=C/CCCCCCCC(=O)OCC(COP(=O)(O)O)O
• InChI: InChI=1S/C21H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h6-7,9-10,20,22H,2-5,8,11-19H2,1H3,(H2,24,25,26)/b7-6+,10-9+
• InChIKey: ZQTAMPRZFOOEEP-AVQMFFATSA-N

名称和登记号

名称

• IUPAC标准名: [2-hydroxy-3-(octadeca-9,12-dienoyloxy)propoxy]phosphonic acid; {2-hydroxy-3-[(9E,12E)-octadeca-9,12-dienoyloxy]propoxy}phosphonic acid
• IUPAC传统名: 2-hydroxy-3-(octadeca-9,12-dienoyloxy)propoxyphosphonic acid; 2-hydroxy-3-[(9E,12E)-octadeca-9,12-dienoyloxy]propoxyphosphonic acid
• 别名: Anti-Platelet-activating factor acetylhydrolase; Anti-Lissencephaly 1; Anti-PAFAH; Anti-LIS1 antibody produced in rabbit; Monoclonal Anti-LIS1 antibody produced in mouse

登记号

• MDL号: MFCD03457563
• PubChem SID: 162227990; 24896475
• PubChem CID: 5795880
• NCBI accession number: P43034

理论计算性质

• Acid pKa: 1.5053178
• 质子受体: 5
• 质子供体: 3
• LogD (pH = 5.5): 2.7191758
• LogD (pH = 7.4): 1.8368158
• Log P: 5.123768
• 摩尔折射率: 116.4156 cm^3
• 极化性: 45.21914 Å^3
• 极化表面积: 113.29 Å^2
• 可自由旋转的化学键: 20
• 里宾斯基五规则: false

分子性质

理化性质

• 外观: buffered aqueous solution

安全信息

• 德国WGK号: -; 3
• 保存温度: -20°C

药理学性质

• 相关基因信息: human ... PAFAH1B1(5048); human ... PAFAH1B1(5048)mouse ... Pafah1b1(18472)rat ... Pafah1b1(83572)

产品相关信息

• 浓度: ~2 mg/mL
• 应用领域: immunocytochemistry: suitable; immunoprecipitation: suitable; indirect ELISA: suitable; microarray: suitable; western blot: 0.5-1 μg/mL using a rat brain cytosol preparation; western blot: suitable
• 运输包装: dry ice
• 克隆类型: LIS1-338, monoclonal; polyclonal
• 物种反应性: bovine, chicken, human, rat, mouse, zebrafish; human, mouse, rat
• 抗体形式: affinity isolated antibody; purified immunoglobulin
• 同种型: IgG1
• Mol. Weight: antigen mol wt 46 kDa

详细说明

Sigma Aldrich - SAB3500302

Immunogen
LIS1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human LIS1.
Physical form
Supplied in PBS with 0.02% sodium azide.

Sigma Aldrich - L7391

Immunogen
recombinant human LIS1 protein.
Specificity
By immunoblotting, the antibody prefers the phosphorylated form of the LIS1 molecule (46 kDa).
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.