{[(2,6-dimethylphenyl)carbamoyl]methyl}triethylazanium chloride

• ChemBase编号: 132930
• 分子式: C16H27ClN2O
• 平均质量: 298.85138
• 单一同位素质量: 298.18119117
• SMILES: CC[N+](CC)(CC)CC(=O)Nc1c(cccc1C)C.[Cl-]
• Canonical SMILES: CC[N+](CC(=O)Nc1c(C)cccc1C)(CC)CC.[Cl-]
• InChI: InChI=1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
• InChIKey: LLPPOMUAOGMYQI-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: {[(2,6-dimethylphenyl)carbamoyl]methyl}triethylazanium chloride
• IUPAC传统名: {[(2,6-dimethylphenyl)carbamoyl]methyl}triethylazanium chloride
• 别名: N-(2,6-Dimethylphenylcarbamoylmethyl) triethylammonium chloride; Lidocaine N-ethyl chloride

登记号

• MDL号: MFCD01669894
• PubChem SID: 24896288; 162227207
• PubChem CID: 21462

理论计算性质

• Acid pKa: 12.140139
• 质子受体: 1
• 质子供体: 1
• LogD (pH = 5.5): -0.9626092
• LogD (pH = 7.4): -0.9621279
• Log P: -0.9626153
• 摩尔折射率: 94.5918 cm^3
• 极化性: 31.261957 Å^3
• 极化表面积: 29.1 Å^2
• 可自由旋转的化学键: 6
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble

安全信息

• 保存条件: protect from light
• 德国WGK号: 3
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: room temp

详细说明

Sigma Aldrich - L1663

Biochem/physiol Actions
Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker.
Other Notes
Stable at room temperature lyophilized. In solution, store at 4 °C for up to two weeks. Store solutions at -20 °C for up to six months.