2,6-diaminohexanoic acid hydrobromide

• ChemBase编号: 132449
• 分子式: C6H15BrN2O2
• 平均质量: 227.0995
• 单一同位素质量: 226.03168973
• SMILES: C(CCN)CC(C(=O)O)N.Br
• Canonical SMILES: NCCCCC(C(=O)O)N.Br
• InChI: InChI=1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
• InChIKey: MEXAGTSTSPYCEP-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 2,6-diaminohexanoic acid hydrobromide
• IUPAC传统名: lysine hydrobromide
• 别名: 多聚-D-赖氨酸 氢溴酸盐; 多聚-D-赖氨酸氢溴酸盐; 聚-DL-赖氨酸 氢溴酸盐; PDL; Poly-D-lysine hydrobromide; Poly-DL-lysine hydrobromide

登记号

• CAS号: 73565-55-6; 27964-99-4
• MDL号: MFCD00131934
• PubChem SID: 24898137; 24898143; 24898091; 24898763; 24898884; 24898835; 24898848; 24898164; 24898537; 162226726; 24898764
• PubChem CID: 16219815

理论计算性质

• Acid pKa: 2.7382863
• 质子受体: 4
• 质子供体: 3
• LogD (pH = 5.5): -5.9555907
• LogD (pH = 7.4): -4.978252
• Log P: -3.2145348
• 摩尔折射率: 37.8095 cm^3
• 极化性: 15.365045 Å^3
• 极化表面积: 89.34 Å^2
• 可自由旋转的化学键: 5
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: lyophilized powder

安全信息

• 德国WGK号: 3
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C

产品相关信息

• 适用性: suitable for cell culture
• 无菌消毒: γ-irradiated
• 产品质量级别: PREMIUM
• Mol. Weight: average mol wt 30,000-70,000; average Mv >70,000; average Mv 1,000-4,000; mol wt >300,000; mol wt ≥300,000; mol wt 1,000-5,000; mol wt 15,000-30,000; mol wt 150,000-300,000; mol wt 30,000-70,000; mol wt 4,000-15,000; mol wt 70,000-150,000
• 线性分子式: D-Lys-(D-Lys)/n-D-Lys · xHBr; D-Lys-(D-Lys)n-D-Lys · xHBr

详细说明

Sigma Aldrich - P6407

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Molecular weight based on viscosity.
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a higher binding site density, but is more viscous than P7280. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.

Sigma Aldrich - P4408

Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P7405

Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

Sigma Aldrich - P7280

Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a lowerer binding site density, but is less viscous than P6407. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher the molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.

Sigma Aldrich - P1149

Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P7886

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P6403

Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P1024

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P0899

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P0296

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - 81358

Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
Useful for promoting cell adhesion to solid substances1
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.