bis(3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine) dichlorozinc dihydrochloride

• ChemBase编号: 132355
• 分子式: C34H40Cl4N6Zn
• 平均质量: 739.9136
• 单一同位素质量: 736.13599803
• SMILES: CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C.CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C.Cl.Cl.Cl[Zn]Cl
• Canonical SMILES: CN(c1ccc2c(c1)nc1c(c2)ccc(c1)N(C)C)C.CN(c1ccc2c(c1)nc1c(c2)ccc(c1)N(C)C)C.Cl[Zn]Cl.Cl.Cl
• InChI: InChI=1S/2C17H19N3.4ClH.Zn/c2*1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;;;;;/h2*5-11H,1-4H3;4*1H;/q;;;;;;+2/p-2
• InChIKey: RAHGLSRJKRXOSY-UHFFFAOYSA-L

名称和登记号

名称

• IUPAC标准名: bis(3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine) dichlorozinc dihydrochloride
• IUPAC传统名: bis(acridine orange) zinc chloride dihydrochloride
• 别名: 3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt; 3,6-Bis(dimethylamino)acridinium chloride hemi(zinc chloride salt); Basic Orange 14; Acridine Orange hemi(zinc chloride) salt

登记号

• CAS号: 10127-02-3
• EC号: 233-353-6
• MDL号: MFCD00081043
• Beilstein号: 3734978
• PubChem SID: 162226632; 24891048; 24849765
• PubChem CID: 16211342
• Color Index Number: 46005

理论计算性质

• 质子受体: 3
• 质子供体: 0
• LogD (pH = 5.5): 2.0666623
• LogD (pH = 7.4): 2.9319835
• Log P: 3.7223153
• 摩尔折射率: 84.9147 cm^3
• 极化性: 34.26807 Å^3
• 极化表面积: 19.37 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: false

分子性质

理化性质

• 紫外吸收波长: λmax 489 nm

安全信息

• 德国WGK号: 3
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品相关信息

• 级别: for microscopy (Fl., Hist.); for molecular biology
• 主要成分: Dye content, ~80%; Dye content, 90%
• 线性分子式: C17H20ClN3 · HCl · 1/2ZnCl2

详细说明

Sigma Aldrich - A6014

Application
Acridine orange has been used as a fluorescent stain for nucleic acids in agarose and polyacrylamide gels. Acridine orange at a concentration of 120 μM will detect purified DNA in gels with a sensitivity of 25-50 ng per band. It has also been used extensively for cell staining of DNA in apoptosis studies.
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.
包装
10, 25, 100 g in glass bottle

Sigma Aldrich - 01660

Other Notes
Versatile probe of nucleic acids and other cell constituents1
Application
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

Sigma Aldrich - 158550

Application
Biological stain
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.
包装
10, 25, 100 g in glass bottle