disodium 2-(phosphonatooxy)propane-1,3-diol hydrate

• ChemBase编号: 131815
• 分子式: C3H9Na2O7P
• 平均质量: 234.052661
• 单一同位素质量: 233.98812782
• SMILES: C(C(CO)OP(=O)([O-])[O-])O.O.[Na+].[Na+]
• Canonical SMILES: OCC(OP(=O)([O-])[O-])CO.O.[Na+].[Na+]
• InChI: InChI=1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
• InChIKey: ROPZSVKNEIIIDE-UHFFFAOYSA-L

名称和登记号

名称

• IUPAC标准名: disodium 2-(phosphonatooxy)propane-1,3-diol hydrate
• IUPAC传统名: disodium glycerol 2-phosphate hydrate
• 别名: 甘油-2-磷酸 二钠盐 水合物; β-甘油磷酸 二钠盐 水合物; 甘油磷酸酯 二钠盐 水合物; BGP; β-Glycerophosphate disodium salt hydrate; Glycerophosphate disodium salt hydrate; Glycerol phosphate disodium salt hydrate; Glycerol 2-phosphate disodium salt hydrate

登记号

• CAS号: 154804-51-0; 55073-41-1
• EC号: 212-464-3
• MDL号: MFCD00149082
• PubChem SID: 24895383; 162226092; 24895257; 24895253; 24895249
• PubChem CID: 16219387

理论计算性质

• Acid pKa: 1.1346252
• 质子受体: 5
• 质子供体: 2
• LogD (pH = 5.5): -4.4191055
• LogD (pH = 7.4): -5.5677385
• Log P: -1.9625801
• 摩尔折射率: 29.1456 cm^3
• 极化性: 12.625253 Å^3
• 极化表面积: 112.88 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: powder
• 熔点: 102-104 °C(lit.)

安全信息

• RTECS编号: UA0600000
• 德国WGK号: 3
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品相关信息

• 纯度: ≥99.0% (titration)
• 适用性: suitable for cell culture; suitable for plant cell culture
• 杂质: ≤0.1% Inorganic phosphorus; ≤0.1% Insoluble matter; ≤0.20% L-α-isomer; ≤0.20% α-isomer; ≤0.5 mol % L-α-isomer; ≤1.0 mol % L-α-isomer; ≤2.4 mol % α-isomer((based on C3H7O6PNa2 With x H2O))
• 痕量阳离子: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.005%; Mg: ≤0.0005%; Pb: ≤0.001%; Zn: ≤0.0005%
• 痕量阴离子: chloride (Cl-): ≤0.05%; sulfate (SO42-): ≤0.05%
• 生物来源: from synthetic
• 产品线: BioUltra
• 线性分子式: (HOCH2)2CHOP(O)(ONa)2 · xH2O

详细说明

Sigma Aldrich - G5422

Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Sigma Aldrich - G9891

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
Glycero-2-phosphate is a component of dexamethasone based hormone cocktail used to induce mesechymal stem cell (MSC) differentiation into osteoblasts.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Sigma Aldrich - G6376

Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Sigma Aldrich - G6501

Application
Evaluated as phosphorus source in the cultivation of Pichia pastoris.1 Used along with chitosan to prepare biodegradable hydrogels.2
Physical form
Usually contains 50% β-isomer and 50% rac-α-isomer

Sigma Aldrich - G9422

Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Sigma Aldrich - G6251

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.