(2R,3R,4S,5R,6R)-2-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

• ChemBase编号: 131453
• 分子式: C24H47NO7
• 平均质量: 461.63248
• 单一同位素质量: 461.33525285
• SMILES: CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O)N)O
• Canonical SMILES: CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O)N)O
• InChI: InChI=1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21-,22-,23+,24+/m0/s1
• InChIKey: HHJTWTPUPVQKNA-PIIMIWFASA-N

名称和登记号

名称

• IUPAC标准名: (2R,3R,4S,5R,6R)-2-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
• IUPAC传统名: psychosine
• 别名: 1-β-D-Galactosylsphingosine; Psychosine from bovine brain; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl α-D-Galactopyranoside; α-Galactosyl erythro-Sphingosine

登记号

• CAS号: 2238-90-6
• MDL号: MFCD00057505
• PubChem SID: 24899021; 162225731
• PubChem CID: 5280458

理论计算性质

• Acid pKa: 12.206499
• 质子受体: 8
• 质子供体: 6
• LogD (pH = 5.5): -0.13794628
• LogD (pH = 7.4): 1.0860742
• Log P: 2.7957444
• 摩尔折射率: 124.3053 cm^3
• 极化性: 49.999756 Å^3
• 极化表面积: 145.63 Å^2
• 可自由旋转的化学键: 18
• 里宾斯基五规则: false

分子性质

理化性质

• 溶解度: Dichloromethane; Methanol
• 外观: lyophilized powder; White to off-white solid
• 熔点: 205-208°C

安全信息

• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 德国WGK号: 3
• 危险公开号: 20/21/22
• 安全公开号: 36
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H302-H312-H332
• GHS警示性声明: P280
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 保存温度: -20°C

产品相关信息

• 纯度: ≥98% (TLC)

详细说明

Sigma Aldrich - P9256

Biochem/physiol Actions
Glycolipid precursor of cerebrosides
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P9256.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Toronto Research Chemicals - G185075

Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity