disodium hydrogen phosphate

• ChemBase编号: 130837
• 分子式: HNa2O4P
• 平均质量: 141.958841
• 单一同位素质量: 141.9407837
• SMILES: OP(=O)([O-])[O-].[Na+].[Na+]
• Canonical SMILES: [O-]P(=O)(O)[O-].[Na+].[Na+]
• InChI: InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
• InChIKey: BNIILDVGGAEEIG-UHFFFAOYSA-L

名称和登记号

名称

• IUPAC标准名: disodium hydrogen phosphate
• IUPAC传统名: disodium hydrogen phosphate
• 别名: 无水磷酸氢二钠, ACS; 二盐基性磷酸钠 溶液; 磷酸二钠 溶液; 磷酸氢二钠 溶液; 磷酸根 IC 标准溶液; 二盐基磷酸钠; 磷酸一氢钠; 磷酸二钠; 磷酸氢二钠; 磷酸钠 二元; 磷酸氢二钠 溶液; 磷酸根离子，认证阴离子标准液 溶液; 磷酸氢二钠; Sodium hydrogen phosphate, anhydrous, ACS; Disodium hydrogen phosphate solution; di-Sodium hydrogen phosphate solution; Sodium phosphate dibasic solution; Phosphate Standard for IC; sec-Sodium phosphate; Disodium hydrogen phosphate; Disodium phosphate; Sodium hydrogenphosphate; Sodium phosphate dibasic; Sodium phosphate dibasic solution; Phosphate, certified anion standard solution; Dinatrii phosphas anhydricus; Sodium phosphate, dibasic; Sodium hydrogen phosphate

登记号

• CAS号: 7558-79-4
• EC号: 231-448-7; 231-791-2
• MDL号: MFCD00003496
• 默克索引号: 148659
• PubChem SID: 24899559; 24901046; 24899638; 24886240; 24845716; 24899856; 24887682; 24886237; 24899552; 24899448; 162225115; 24889758; 24855481; 24858358; 24899769
• PubChem CID: 24203
• FEMA编号: 2399

理论计算性质

• Acid pKa: 1.7961261
• 质子受体: 4
• 质子供体: 1
• LogD (pH = 5.5): -3.3916447
• LogD (pH = 7.4): -3.9718332
• Log P: -1.0201038
• 摩尔折射率: 12.4085 cm^3
• 极化性: 5.685633 Å^3
• 极化表面积: 83.42 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble0.5 M at 20 °C, clear, colorless; H2O: soluble1 M at 20 °C, clear, colorless; H2O: soluble100 mg/mL
• 外观: Granular; powder; solid
• 密度: 1.064 g/mL at 20 °C
• 蒸汽密度: 4.9 (vs air)
• 紫外吸收波长: A1M/260, H2O <0.05; A1M/280, H2O <0.05; λ: 220 nm Amax: 0.1; λ: 230 nm Amax: 0.05; λ: 240 nm Amax: 0.04; λ: 250 nm Amax: 0.03; λ: 260 nm Amax: ≤0.025; λ: 260 nm Amax: 0.019; λ: 260 nm Amax: 0.02; λ: 280 nm Amax: ≤0.020; λ: 280 nm Amax: 0.016; λ: 500 nm Amax: 0.02; λ: 500 nm Amax: 0.03
• pKa: (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid); (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid) (25°C)
• pH值: 8.0-11.0 (20 °C, 1 M in H2O); 8.4-9.6 (20 °C, 1%); 8.7-9.3 (25 °C, 5% in solution); 8.7-9.3 (25 °C, 50 mg/mL in H2O); 8.8-9.4 (25 °C, 0.5 M in H2O); 8.8-9.4 (25 °C, 50 mg/mL in H2O); 8.9-9.2 (20 °C, 5%)

安全信息

• 保存注意事项: Hygroscopic
• RTECS编号: WC4500000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 1; 3; nwg
• 危险公开号: 36/37/38
• 安全公开号: 26; 26-37-60
• TSCA收录: 是
• GHS危险品标识: GHS07
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 个人保护装置: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter; Eyeshields, Gloves; Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Regulation Compliance: FDA 21 CFR (175.210); FDA 21 CFR (175.300); FDA 21 CFR (182.1778); FDA 21 CFR (182.6290)

产品相关信息

• 纯度: ≥98%; ≥98.0% (T); ≥98.5% (titration); ≥99%; ≥99.0%; ≥99.0% (T); ≥99.5%; ≥99.5% (T); ≥99.999% (metals basis); 98+%; 98-100.5% (calc. to the dried substance); 99.0% min; 99.95% trace metals basis
• 浓度: 0.5 M in H2O; 1000 mg/kg PO43-; 1000 mg/L PO43- in H2O
• 级别: ACS reagent; for electrophoresis; for HPLC; for ion chromatography; for molecular biology; for trace analysis; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; ReagentPlus®; SAJ first grade; TraceCERT®; TraceSELECT®
• 适用性: complies for appearance of solution; corresponds to standard for filter test; corresponds to standard for RP gradient test; suitable for cell culture; suitable for electrophoresis buffers for the Weber and Osborn system; suitable for insect cell culture
• 杂质: ≤0.001% heavy metals (as Pb); ≤0.001% total nitrogen (N); ≤0.002% ammonium (NH4); ≤0.002% Chloride (Cl); ≤0.01% Insoluble matter; ≤0.01% insolubles; ≤0.1% Insoluble matter; ≤0.2% water-insoluble matter; ≤1% NaH2PO4(calc. to dried subst.); ≤10 mg/kg total nitrogen (N); ≤2.0% pyrophosphate (as Na4P2O7); DNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected; reducing matter, complies; residual solvents, complies; RNases, none detected
• 痕量阳离子: Al: ≤0.0005%; Al: ≤1 mg/kg; Al: ≤5 mg/kg; As: ≤0.1 mg/kg; As: ≤0.2 mg/kg; As: ≤1 mg/kg; As: ≤2 mg/kg; Ba: ≤1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤1 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.002%; Ca: ≤0.5 mg/kg; Ca: ≤10 mg/kg; Ca: ≤5 mg/kg; Ca: ≤50 mg/kg; Cd: ≤0.01 mg/kg; Cd: ≤1 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Ce: ≤0.01 mg/kg; Co: ≤0.01 mg/kg; Co: ≤1 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤1 mg/kg; Cr: ≤5 mg/kg; Cs: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤0.01 mg/kg; Cu: ≤1 mg/kg; Cu: ≤10 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Eu: ≤0.01 mg/kg; Fe: ≤0.002%; Fe: ≤0.05 mg/kg; Fe: ≤1 mg/kg; Fe: ≤20 mg/kg; Fe: ≤20 ppm; Fe: ≤5 mg/kg; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤0.001%; heavy metals (as Pb): ≤10 ppm; heavy metals: ≤0.001%; Hg: ≤0.005 mg/kg; Hg: ≤1 mg/kg; K: ≤0.005%; K: ≤100 mg/kg; K: ≤2 mg/kg; K: ≤20 mg/kg; K: ≤200 mg/kg; K: ≤50 mg/kg; La: ≤0.01 mg/kg; Li: ≤1 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.005%; Mg: ≤0.1 mg/kg; Mg: ≤1 mg/kg; Mg: ≤5 mg/kg; Mn: ≤0.01 mg/kg; Mn: ≤1 mg/kg; Mn: ≤5 mg/kg; Mo: ≤1 mg/kg; Mo: ≤5 mg/kg; NH4+: ≤0.05%; Ni: ≤0.01 mg/kg; Ni: ≤1 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤0.01 mg/kg; Pb: ≤2 mg/kg; Pb: ≤4 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Rb: ≤5 mg/kg; Sm: ≤0.01 mg/kg; Sr: ≤0.5 mg/kg; Sr: ≤1 mg/kg; Sr: ≤5 mg/kg; Tl: ≤0.01 mg/kg; Y: ≤0.01 mg/kg; Yb: ≤0.01 mg/kg; Zn: ≤0.0005%; Zn: ≤0.01 mg/kg; Zn: ≤1 mg/kg; Zn: ≤10 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg
• 痕量阴离子: chloride (Cl-): ≤0.002%; chloride (Cl-): ≤0.05%; chloride (Cl-): ≤10 mg/kg; chloride (Cl-): ≤40 ppm; chloride (Cl-): ≤5 mg/kg; chloride (Cl-): ≤50 mg/kg; fluoride (F-): ≤10 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤0.05%; sulfate (SO42-): ≤1000 mg/kg; sulfate (SO42-): ≤200 mg/kg; sulfate (SO42-): ≤30 mg/kg; sulfate (SO42-): ≤50 mg/kg
• Foreign Activity: DNase, RNase and protease, none detected
• 干燥失重: ≤0.1% loss on drying, 110 °C; ≤0.2% loss on drying; ≤0.2% loss on drying, 105 °C; ≤0.2% loss on drying, 105 °C, 2 h; ≤0.2% loss on drying, 105°C; ≤1% loss on drying, 105°C, 4h; ≤1% loss on drying, 130 °C; ≤2% loss on drying, 110 °C
• pH范围: 8.7 - 9.3
• 产品质量级别: PREMIUM
• 品质说明: ampule; certified by BAM, according to ISO 17025; meets analytical specification of Ph. Eur., BP, USP, FCC, E 339
• λ: 0.5 M in H2O; in concentrate
• 药典: testing & handling conforms to Pharmacopeia
• 产品线: BioUltra
• 线性分子式: Na2HPO4

详细说明

Sigma Aldrich - W239901

包装
1 kg in poly bottle
1 sample in glass bottle
5 kg in poly drum

Sigma Aldrich - 219886

Application
适用于缓冲溶液

Sigma Aldrich - 71639

Other Notes
Primary standard buffer1

Sigma Aldrich - 81193

Analysis Note
精确浓度、有效期、可溯源性以及详细认证信息，请见每个包装内的证书和认证报告。标签上标明含量和有效期。
Preparation Note
用高纯度 Na2HPO4 以及高纯度水（18MOhm，0.22μm 过滤）制备

Sigma Aldrich - 71648

包装
安瓿瓶装浓缩液 (~0.33M)，用于 6×1L 0.005M 即用型溶液
Reconstitution
建议用于离子对色谱

Sigma Aldrich - 38364

Analysis Note
此认证标准物质 (CRM) 是根据 ISO/IEC 17025 和 ISO Guide 34 生产和认证的。此 CRM 可溯源到 SI Unit 和 NIST SRM。经认证的含量包括不确定度和有效期见标签。证书下载：http://www.sigma-aldrich.com。
General description
水中 PO4-3 含量为 1000mg/L，由高纯度 Na2HPO4 和 TraceSELECT®Ultra 水制备。
法律信息
TraceCERT 注册商标 Sigma-Aldrich Co. LLC
TraceSELECT 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 255793

包装
10, 50 g in poly bottle

Sigma Aldrich - 71629

法律信息
TraceSELECT 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 28-3770

Suitability
pH standard solution

Sigma Aldrich - S0876

包装
1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - S9763

包装
1, 2.5 kg in poly bottle
100, 500 g in poly bottle
5, 12 kg in poly drum

Sigma Aldrich - 71651

包装
安瓿瓶装浓缩液 (~0.50M)，用于 6×1L 0.01M 即用型溶液
Reconstitution
建议用于离子对色谱