4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol dihydrochloride

• ChemBase编号: 130728
• 分子式: C8H14Cl2N2O2
• 平均质量: 241.11496
• 单一同位素质量: 240.04323306
• SMILES: Cc1c(c(c(cn1)CO)CN)O.Cl.Cl
• Canonical SMILES: NCc1c(CO)cnc(c1O)C.Cl.Cl
• InChI: InChI=1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H
• InChIKey: HNWCOANXZNKMLR-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol dihydrochloride
• IUPAC传统名: pyridoxamine dihydrochloride
• 别名: 4-(氨甲基)-5-羟基-6-甲基-3-羟甲基吡啶 二盐酸盐; 吡哆胺 二盐酸盐; 4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride; Pyridoxamine dihydrochloride; 4-(Aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol dihydrochloride

登记号

• CAS号: 524-36-7
• EC号: 208-357-6
• MDL号: MFCD00012808
• Beilstein号: 3632748
• PubChem SID: 24857266; 162225006; 24899015; 24888058; 24899030
• PubChem CID: 10664

理论计算性质

• Acid pKa: 7.816021
• 质子受体: 4
• 质子供体: 3
• LogD (pH = 5.5): -3.645828
• LogD (pH = 7.4): -2.061956
• Log P: -1.5896055
• 摩尔折射率: 45.7628 cm^3
• 极化性: 17.63022 Å^3
• 极化表面积: 79.37 Å^2
• 可自由旋转的化学键: 2
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: powder
• 熔点: 224-226 °C (dec.)(lit.)

安全信息

• RTECS编号: UV1230000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 2
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 保存温度: -20°C

产品相关信息

• 纯度: ≥98%; ≥99.0% (TLC); 95+%
• 级别: purum
• 适用性: suitable for cell culture
• 杂质: ≤10% water(may contain); ≤8% water
• Empirical Formula (Hill Notation): C8H12N2O2 · 2HCl

详细说明

Sigma Aldrich - P9158

Application
Use in mammalian cell culture as an alternative to pyridoxine or pyridoxal. Vitamin B6 is a required component of cell culture media. Historically, media have been supplemented with vitamin B6 in the aldehyde form, pyridoxal. While this is a biologically active form of vitamin B6, it is unstable in liquid media. When cells are able to utilize either pyridoxine and/or pyridoxamine, they are preferred supplement versus pyridoxal. A number of classical media are now offered with a choice between pyridoxal and pyridoxine as the vitamin A source.

Sigma Aldrich - 287091

包装
1, 5 g in glass bottle

Sigma Aldrich - P9380

包装
1, 5, 25 g in poly bottle