bis((2S)-1-phenylpropan-2-amine); sulfuric acid

• ChemBase编号: 130715
• 分子式: C18H28N2O4S
• 平均质量: 368.49092
• 单一同位素质量: 368.17697839
• SMILES: C[C@@H](Cc1ccccc1)N.C[C@@H](Cc1ccccc1)N.OS(=O)(=O)O
• Canonical SMILES: OS(=O)(=O)O.C[C@@H](Cc1ccccc1)N.C[C@@H](Cc1ccccc1)N
• InChI: InChI=1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)/t2*8-;/m00./s1
• InChIKey: PYHRZPFZZDCOPH-QXGOIDDHSA-N

名称和登记号

名称

• IUPAC标准名: bis((2S)-1-phenylpropan-2-amine); sulfuric acid
• IUPAC传统名: bis(amphetamine); sulfuric acid
• 别名: D-安非他明 半硫酸盐 溶液; D-安非他明 半硫酸盐; D-Amphetamine hemisulfate salt solution; (+)-α-Methylphenethylamine hemisulfate salt; Dextroamphetamine hemisulfate salt; D-Amphetamine hemisulfate salt

登记号

• CAS号: 51-63-8
• EC号: 200-111-6
• MDL号: MFCD00069209
• PubChem SID: 24891028; 162224993; 24890756
• PubChem CID: 5825

理论计算性质

• 质子受体: 1
• 质子供体: 1
• LogD (pH = 5.5): -1.2147744
• LogD (pH = 7.4): -0.67093694
• Log P: 1.8042505
• 摩尔折射率: 43.7052 cm^3
• 极化性: 17.364613 Å^3
• 极化表面积: 26.02 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: ethanol: soluble; H2O: soluble
• 闪点: 11 °C; 51.8 °F

安全信息

• RTECS编号: SI1400000
• 欧盟危险性物质标志: 易燃性(Flammable) (F); 有毒(Toxic) (T)
• 联合国危险货物编号: 1230; 2811
• 德国WGK号: 1; 3
• 联合国危险货物等级: 3; 6.1
• 联合国危险货物包装类别(PG): 2
• 危险公开号: 11-23/24/25-39/23/24/25; 25
• 安全公开号: 16-36/37-45; 45
• GHS危险品标识: GHS02; GHS06; GHS08
• GHS警示词: Danger
• GHS危险声明: H225-H301-H311-H331-H370; H300
• GHS警示性声明: P210-P260-P280-P301 + P310-P311; P264-P301 + P310
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter; Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• RID/ADR: UN 1230 3/PG 2; UN 2811 6.1/PG 2
• 毒品管制信息: Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; USDEA Schedule II; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• 保存温度: 2-8°C

产品相关信息

• 浓度: 1.0 mg/mL±5% in methanol
• 级别: analytical standard, for drug analysis

详细说明

Sigma Aldrich - A5880

Other Notes
More active isomer of amphetamine
Application
D-Amphetamine induces the release of catecholamines and blocks catecholamine reuptake. D-Amphetamine has also been used to study the extinction of cued fear, as well as the therapeutic implications for learned phobias and post-traumatic stress disorder.
Biochem/physiol Actions
Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.