sodium 2-oxopropanoate

• ChemBase编号: 129553
• 分子式: C3H3NaO3
• 平均质量: 110.04389
• 单一同位素质量: 109.99798824
• SMILES: [Na+].[O-]C(=O)C(=O)C
• Canonical SMILES: CC(=O)C(=O)[O-].[Na+]
• InChI: InChI=1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• InChIKey: DAEPDZWVDSPTHF-UHFFFAOYSA-M

名称和登记号

名称

• IUPAC标准名: sodium 2-oxopropanoate
• IUPAC传统名: sodium 2-oxopropionate; sodium pyruvate
• 别名: α-酮基丙酸 钠盐; 2-氧代丙酸 钠盐; 乙酰甲酸 钠盐; 丙酮酸钠; 丙酮酸钠 溶液; α-ketopropionic acid sodium salt2-oxopropanoic acid sodium saltPyruvic acid sodium salt; Sodium pyruvate; Sodium Pyruvate; Sodium α-Ketopropionate; Pyruvic Acid Sodium Salt; Sodium pyruvate; α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt; Pyruvic acid sodium salt; Sodium pyruvate solution

登记号

• CAS号: 113-24-6
• EC号: 204-024-4
• MDL号: MFCD00002586
• Beilstein号: 3568341
• PubChem SID: 24899804; 24898303; 24898951; 162223844; 24898440; 24898552; 24898615
• PubChem CID: 23662274
• CHEBI ID: 50144
• CHEMBL: 181886
• Chemspider ID: 7931
• 美国药典/FDA物质标识码: POD38AIF08
• 维基百科标题: Sodium_pyruvate

理论计算性质

• Acid pKa: 2.9301233
• 质子受体: 3
• 质子供体: 0
• LogD (pH = 5.5): -2.4600048
• LogD (pH = 7.4): -3.4164543
• Log P: 0.06587395
• 摩尔折射率: 28.8268 cm^3
• 极化性: 6.905475 Å^3
• 极化表面积: 57.2 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 100 mg/mL; H2O: soluble1 M, clear, colorless; H2O: soluble100 mg/mL
• 外观: powder; solution
• 熔点: >300 °C(lit.); >300°C

安全信息

• 德国WGK号: 2; 3
• TSCA收录: 是
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C

产品相关信息

• 纯度: ≥95.0%; ≥99%; ≥99.0% (NT); 99%
• 浓度: 100 mM
• 级别: Hybri-Max™; purum; ReagentPlus®; SAJ special grade
• 适用性: suitable for cell culture; suitable for hybridoma; suitable for insect cell culture; suitable for mouse embryo
• 杂质: ≤0.005% Phosphorus (P); ≤0.1% Insoluble matter; endotoxin, tested
• 痕量阳离子: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH4+: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• 痕量阴离子: chloride (Cl-): ≤0.05%; sulfate (SO42-): ≤0.05%
• 无菌消毒: sterile-filtered
• 产品质量级别: GMP; PREMIUM
• 产品线: BioReagent
• 线性分子式: CH3COCOONa

详细说明

Sigma Aldrich - P5280

Biochem/physiol Actions
Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Sigma Aldrich - S8636

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Sigma Aldrich - P4562

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Sigma Aldrich - P3662

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.
法律信息
Hybri-Max 商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 15990

Other Notes
当存在于培养基中时提高大肠杆菌的回收率1。

Sigma Aldrich - P2256

包装
10 mg in autosmp vl
5, 25, 100, 500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Toronto Research Chemicals - P998900

Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, wh

参考文献

• Wenzel, A., et al.: J. Neurosci., 21, 53 (2001)
• Martinez., et al.: Development, 6, 851 (2001)
• Nakayama, K., et al.: J. Biochem., 146, 757 (2001)
• Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2001)