N-(prop-2-enamidomethyl)prop-2-enamide

• ChemBase编号: 128490
• 分子式: C7H10N2O2
• 平均质量: 154.1665
• 单一同位素质量: 154.07422757
• SMILES: C=CC(=O)NCNC(=O)C=C
• Canonical SMILES: C=CC(=O)NCNC(=O)C=C
• InChI: InChI=1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
• InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: N-(prop-2-enamidomethyl)prop-2-enamide
• IUPAC传统名: N,N'-methylenebisacrylamide
• 别名: N,N′-亚甲基双丙烯酰胺 溶液; N,N′-亚甲基双丙烯酰胺; 甲叉双丙烯酰胺; N,N'-亚甲基双丙烯酰胺; N-(prop-2-enamidomethyl)prop-2-enamide; N,N′-Methylenebisacrylamide solution; N,N'-Methylenebisacrylamide; BIS; N,N′-Methylenebisacrylamide; Bis-acrylamide; N,N′-Methylenebis(acrylamide); BAC; N,N'-Methylenebisacrylamide

登记号

• CAS号: 110-26-9
• EC号: 203-750-9
• MDL号: MFCD00008625
• Beilstein号: 1706297
• PubChem SID: 162222797; 24896597; 24897151; 24848761; 24896663; 24884814; 24897148
• PubChem CID: 8041
• 维基百科标题: N,N'-Methylenebisacrylamide

理论计算性质

• Acid pKa: 13.675445
• 质子受体: 2
• 质子供体: 2
• LogD (pH = 5.5): -0.16206302
• LogD (pH = 7.4): -0.16206253
• Log P: -0.16206251
• 摩尔折射率: 40.8611 cm^3
• 极化性: 15.584384 Å^3
• 极化表面积: 58.2 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble20 mg/mL at 20 °C, clear, colorless
• 外观: powder; Powder
• 熔点: >300 °C(lit.); >300°C; ≥300 °C; 299 - 300°C
• 密度: 1.235
• 蒸汽密度: 5.31 (vs air)
• 紫外吸收波长: A1%/290 ≤0.2
• 疏水性(logP): -0.943
• 电导率: <10 μmho (2% solution); <5 μS/cm at 20 °C (50 mg/ml water); ≤10 μmho (2% solution)

安全信息

• RTECS编号: AS3678000
• 欧盟危险性物质标志: X; 有害性(Harmful) (Xn)
• 德国WGK号: 1; 2
• 危险公开号: 20/22; 22
• 安全公开号: 22; 36-60
• TSCA收录: 是
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H302; H302-H332
• GHS警示性声明: P264-P270-P301+P312-P330-P501A
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves; Eyeshields, Faceshields, Gloves; Eyeshields, Faceshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• 保存温度: 2-8°C

产品相关信息

• 纯度: ≥98%; ≥98.0% (T); ≥99%; ≥99.0%; ≥99.0% (T); ≥99.5%; ≥99.5% (T); 95%; 97%; 99%; 99+%
• 浓度: 2% in H2O
• 级别: electrophoresis grade; for electrophoresis; for molecular biology; purum
• 适用性: in accordance for electrophoresis test; suitable for electrophoresis (after filtration or allowing insolubles to settle)
• 杂质: <0.1% Acrylic acid content; ≤0.05% free acrylic acid; ≤0.05% Free carboxylic acid (T); ≤50 mg/kg Total sulfur (as SO4 ) (ICP); DNases, none detected; phosphatases, none detected; proteases, none detected; RNases, none detected
• 痕量阳离子: Ca: ≤10 mg/kg; Ca: ≤10 ppm; Cd: ≤5 mg/kg; Cd: ≤5 ppm; Co: ≤5 mg/kg; Co: ≤5 ppm; Cr: ≤5 mg/kg; Cr: ≤5 ppm; Cu: ≤5 mg/kg; Cu: ≤5 ppm; Fe: <40 ppm; Fe: ≤5 mg/kg; Fe: ≤5 ppm; K: ≤50 mg/kg; K: ≤50 ppm; Mg: <40 ppm; Mg: ≤5 mg/kg; Mg: ≤5 ppm; Mn: ≤5 mg/kg; Mn: ≤5 ppm; Na: ≤50 mg/kg; Na: ≤50 ppm; Ni: ≤5 mg/kg; Ni: ≤5 ppm; Pb: ≤10 mg/kg; Pb: ≤5 mg/kg; Pb: ≤5 ppm; Zn: ≤5 mg/kg; Zn: ≤5 ppm
• 痕量阴离子: chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): ≤50 mg/kg
• Foreign Activity: DNase and RNase, none detected; DNase, RNase, NICKase and protease, none detected
• 无菌消毒: 0.2 μm filtered
• 线性分子式: (CH2=CHCONH)2CH2; (H2C=CHCONH)2CH2

详细说明

Sigma Aldrich - M1533

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。
Preparation Note
由电泳级甲叉双丙烯酰胺在超纯水中制备。

Sigma Aldrich - M7256

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。
Other Notes
Cross-linking agent, for the preparation of polyacrylamide (from 01698 Acrylamide puriss.) used as gel in electrophoresis for the separation, analysis and characterization of nucleic acids, proteins and other charged species1; A.H. Gordon, Electrophoresis of Proteins in Polyacrylamide and Starch Gels, Vol. 1, Part. I, of "Laboratory Techniques in Biochemistry and Mol. Biology"2.

Sigma Aldrich - M7279

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。
包装
25, 100, 250 g in poly bottle

Sigma Aldrich - M2022

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。

Sigma Aldrich - 19-3180

Suitability
for electrophoresis

Sigma Aldrich - 66667

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。
Other Notes
用于聚丙烯酰胺凝胶的制备1

Sigma Aldrich - 66669

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。
Other Notes
交联剂，用于由 01698 Acrylamide puriss. 制备聚丙烯酰胺。用作电泳中的凝胶，用于核酸、蛋白质和其他带电粒种的分离、分析及表征1,2,3

Sigma Aldrich - 146072

Application
用于制备聚丙烯酰胺的交联剂。
包装
100, 500 g in poly bottle

Sigma Aldrich - 66670

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。

Sigma Aldrich - 148326

包装
100 g in poly bottle

Sigma Aldrich - 66675

Application
与丙烯酰胺混合以制备聚丙烯酰胺凝胶，用于蛋白质和核酸电泳。

参考文献

• Crosslinking agent for the synthesis of polyacrylamide gels.