(2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol

• ChemBase编号: 127575
• 分子式: C6H12O6
• 平均质量: 180.15588
• 单一同位素质量: 180.0633881
• SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
• Canonical SMILES: OC[C@H]1O[C@H](O)[C@@H]([C@H]([C@@H]1O)O)O
• InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N

名称和登记号

名称

• IUPAC标准名: (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
• IUPAC系统名: (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal
• IUPAC传统名: α-glucose
• 别名: D-(+)-葡萄糖, 无水的; α-D-葡萄糖; D-(+)-葡萄糖; 右旋糖; 糊精 来源于玉米; 糊精 来源于马铃薯淀粉; D-(+)-葡萄糖 溶液; 右旋糖; D-(+)-葡萄糖; 无水右旋糖（葡萄糖）; D-(+)-Glucose, anhydrous; D-(+)-Glucose; Glucose solution; alpha-D-Glucose; α-D-Glucose; Dextrose; Dextrin from corn; Blood sugar; Dextrose; Corn sugar; D-Glucose; Grape sugar; Glucose; Dextrin from potato starch; D-(+)-Glucose solution; D-(+)-Glucose; Dextrosum (Glucosum) anhydricum; D-(+)-Glucose solution; Glucose stock solution

登记号

• CAS号: 50-99-7; 9004-53-9; 492-62-6
• EC号: 207-757-8; 231-791-2; 232-675-4; 200-075-1
• MDL号: MFCD00063774; MFCD00081554
• Beilstein号: 1724615; 1281604; 1281608
• 默克索引号: 144459
• PubChem SID: 24872672; 24895228; 24895248; 24893590; 24858935; 24895121; 24893634; 24895199; 162221894; 24858939; 24895346; 24893670; 24895335; 24893904; 24894185; 24895351; 24895286; 24895209; 24850031; 24895314; 24894295; 24872363; 24895311; 24849781; 24870804
• PubChem CID: 79025; 5793
• CHEBI ID: 4167
• ATC码: V04CA02; V06DC01; B05CX01
• CHEMBL: 1222250
• Chemspider ID: 5589
• Gmelin ID: 83256
• KEGG ID: C00031
• 医学主题词(MeSH): Glucose
• 美国药典/FDA物质标识码: 5SL0G7R0OK
• 维基百科标题: Glucose

理论计算性质

• Acid pKa: 11.298101
• 质子受体: 6
• 质子供体: 5
• LogD (pH = 5.5): -2.93254
• LogD (pH = 7.4): -2.932594
• Log P: -2.9325392
• 摩尔折射率: 35.9234 cm^3
• 极化性: 15.155883 Å^3
• 极化表面积: 110.38 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 91 g/100 mL in water; H2O: soluble0.1 g/mL, clear, colorless; H2O: soluble0.1 g/mL, clear, yellow to very deep yellow (hot); H2O: soluble0.13 g/mL; H2O: soluble1 M at 20 °C, clear, colorless; H2O: soluble1 M, clear, colorless
• 外观: off-white to yellow powder; powder; solution; White powder; white powder; yellow powder
• 熔点: 147-153°C; 150-152 °C(lit.); 153-156 °C(lit.); α-D-glucose: 146 °C; β-D-glucose: 150 °C
• 密度: 1.54 g/cm^3
• 折射率: n20/D 1.362
• 比旋光度: [α]20/D +52.5 to +53.3°, c = 10% in H2O (calc. on anhydrous subst.); [α]20/D +52°, c = 10 in H2O; [α]20/D +53±2°, 3 hr, c = 10 in H2O(lit.); [α]20/D +53±2°, 3 hr, c = 10% in H2O; [α]20/D +53±3°, 3 hr, c = 10% in H2O; [α]25/D +52.5 to +53.0°(lit.); +53 (c=10 in water, 3h)
• 紫外吸收波长: A1M/260, H2O ≤0.02; A1M/280, H2O ≤0.03; λ: 260 nm Amax: 0.02; λ: 260 nm Amax: 0.04; λ: 280 nm Amax: 0.03; λ: 280 nm Amax: 0.04
• 标准摩尔燃烧焓 (ΔcH^o298): -2805 kJ/mol
• 标准摩尔生成焓 (ΔfH^o298): -1271 kJ/mol
• 标准摩尔熵 (S^o298): 209.2 J K^-1 mol^-1
• pH值: 5.0-7.0 (25 °C, 1 M in H2O); 6.0-8.0 (25 °C)

安全信息

• RTECS编号: HH9450000; LZ6600000
• 德国WGK号: 1; 3; nwg
• TSCA收录: 是
• 欧盟危险品索引: not listed
• NFPA704:
  

  1

  0

  0
• 个人保护装置: Eyeshields, Gloves; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US); Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C

药理学性质

• 相关基因信息: human ... PYGM(5837)

产品相关信息

• 纯度: ≥98.0%; ≥98.0% (sum of enantiomers, HPLC); ≥99% (GC); ≥99.0% (sum of enantiomers, HPLC); ≥99.5%; ≥99.5% (GC); ≥99.5% (sum of enantiomers, HPLC); 96%; 99%
• 浓度: ~20% in H2O; 1 mg/mL in 0.1% benzoic acid; 100 g/L in H2O; 1000 mg/dL; 45% in H2O
• 级别: ACS reagent; analytical standard; anhydrous; commercial grade; CP; for biotechnological purposes; for microbiology; for molecular biology; Hybri-Max™; JIS special grade; Ph Eur; SAJ first grade
• 包装: ampule of 500 mg
• 适用性: complies for appearance of solution; meets EP, BP, JP, USP testing specifications; plant cell culture tested; suitable for cell culture; suitable for component for culture media; suitable for hybridoma; suitable for insect cell culture; suitable for mouse embryo; suitable for plant cell culture
• 燃烧残渣: ≤0.02%; ≤0.1% (as SO4)
• 杂质: ≤0.001% sulfite (SO2); ≤0.002 meq/g Titratable acid; ≤0.005% Insoluble matter; ≤1% water (Karl Fischer); ≤5% Reducing sugar; acidity or alkalinity, complies; dextrine, complies; DNases, none detected; endotoxin, tested; foreign sugar, complies; Insoluble matter, passes filter test; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected; residual solvents, complies; RNases, none detected; soluble starch, complies; Starch, passes test
• 痕量阳离子: Al: ≤0.0005%; Al: ≤1 mg/kg; Al: ≤5 mg/kg; As: ≤0.0001%; As: ≤0.1 mg/kg; As: ≤1 mg/kg; Ba: ≤0.0005%; Ba: ≤1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤0.0005%; Bi: ≤1 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.001%; Ca: ≤10 mg/kg; Ca: ≤200 mg/kg; Ca: ≤5 mg/kg; Cd: ≤0.0005%; Cd: ≤1 mg/kg; Cd: ≤5 mg/kg; Co: ≤0.0005%; Co: ≤1 mg/kg; Co: ≤5 mg/kg; Cr: ≤0.0005%; Cr: ≤1 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤1 mg/kg; Cu: ≤5 mg/kg; Fe: ≤0.0005%; Fe: ≤1 mg/kg; Fe: ≤5 mg/kg; Fe: ≤5 ppm; heavy metals (as Pb): ≤5 ppm; K: ≤0.005%; K: ≤20 mg/kg; K: ≤50 mg/kg; Li: ≤0.0005%; Li: ≤1 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤1 mg/kg; Mg: ≤5 mg/kg; Mn: ≤0.0005%; Mn: ≤1 mg/kg; Mn: ≤5 mg/kg; Mo: ≤0.0005%; Mo: ≤1 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.005%; Na: ≤20 mg/kg; Na: ≤50 mg/kg; Ni: ≤0.0005%; Ni: ≤1 mg/kg; Ni: ≤5 mg/kg; Pb: ≤0.0005%; Pb: ≤0.5 mg/kg; Pb: ≤1 mg/kg; Pb: ≤5 mg/kg; Sr: ≤0.0005%; Sr: ≤1 mg/kg; Sr: ≤5 mg/kg; Zn: ≤0.0005%; Zn: ≤1 mg/kg; Zn: ≤5 mg/kg
• 痕量阴离子: chloride (Cl-): ≤0.005%; chloride (Cl-): ≤0.01%; chloride (Cl-): ≤100 mg/kg; chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤200 mg/kg; sulfate (SO42-): ≤50 mg/kg; sulfate, sulfite (as SO42-): ≤0.005%
• 无菌消毒: sterile-filtered
• 干燥失重: ≤0.1% loss on drying; ≤0.1% loss on drying, 20 °C (HV); ≤0.2% loss on drying, 105°C
• 产品类型: Type I; Type II; Type III; Type IV
• 产品质量级别: GMP; PREMIUM
• 品质说明: meets analytical specification of Ph. Eur., BP
• λ: 1 M in H2O; neat
• 药典: testing & handling conforms to Pharmacopeia
• 产品线: BioUltra
• Pharmacopeia Traceability: traceable to PhEur G0350500; traceable to USP 1181302
• 线性分子式: (C6H12O6)x
• Empirical Formula (Hill Notation): C6H12O6

详细说明

Sigma Aldrich - D2006

包装
1 kg in poly bottle
100, 500 g in poly bottle
Preparation Note
This grade is prepared by removing a minimum of 95% of the water-insolubles, and almost all of the alcohol-solubles.
Application
Dextrins from corn starch are used in nutrition studies to understand the effects of fiber in diets on energy levels, intestinal flora, digestion and other physiological processes.

Sigma Aldrich - G7528

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
包装
10 mg in autosmp vl

Sigma Aldrich - G7021

Application
Provides the primary energy source for cell metabolism.
Other Notes
Mixed anomers

Sigma Aldrich - G8769

Application
为细胞代谢提供初级能源。

Sigma Aldrich - 49139

Other Notes
Neutralizes growth inhibition by myxothiazol in Saccharomyces cerevisiae, Mucor hiemalis and Candida albicans1; Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers2
Application
D-(+)-Glucose is a common natural sugar involved in processes such as energy production, glycosylation, and formation of glycans that provide structure to cells. Glucose is involved in a detrimentatl process in cells called glycation. Glucose is used as a supplement for cell culture and in numerous cellular processes.

Sigma Aldrich - G6152

Other Notes
Mixed anomers
Application
This glucose has been qualified for use in mouse embryo in vitro work.

Sigma Aldrich - D4894

Analysis Note
Approx. 40% water-soluble; less than 2% alcohol-soluble
Application
Dextrins from potato starch are used in nutrition studies to understand the effects of fiber in diets on energy levels, intestinal flora, digestion and other physiological processes.

Sigma Aldrich - G8644

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Provides the primary energy source for cell metabolism.

Sigma Aldrich - 49163

Application
D-(+)-Glucose is a common natural sugar involved in processes such as energy production, glycosylation, and formation of glycans that provide structure to cells. Glucose is involved in a detrimentatl process in cells called glycation. Glucose is used as a supplement for cell culture and in numerous cellular processes and molecular biology applications.

Sigma Aldrich - G5146

Application
Provides the primary energy source for cell metabolism.
法律信息
Hybri-Max 商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - D2131

Application
Dextrins from corn starch are used in nutrition studies to understand the effects of fiber in diets on energy levels, intestinal flora, digestion and other physiological processes.

Sigma Aldrich - G5400

Analysis Note
已测试用作 M9 低盐培养基中 Escherichia coli (ATCC 25922) 的唯一碳源。

Sigma Aldrich - D2256

Analysis Note
Approx. 75% water-soluble.

Sigma Aldrich - G7520

Other Notes
Mixed anomers
Application
D-(+)-Glucose (G7520) is plant cell culture tested (15 mg/ml) and is appropriate for use in plant cell culture experiments.

Sigma Aldrich - G3285

Analysis Note
可溯源到 NIST 标准
Other Notes
葡萄糖 (GO) 测定试剂盒 (GAGO-20) 的组分。

Sigma Aldrich - 158968

包装
1, 2.5, 3 kg in poly bottle
25, 100, 500 g in poly bottle

Sigma Aldrich - G5767

包装
25, 500 g in poly bottle
5 kg in poly drum