[2-(5-methoxy-1H-indol-3-yl)ethyl]bis(propan-2-yl)amine

• ChemBase编号: 1248
• 分子式: C17H26N2O
• 平均质量: 274.40114
• 单一同位素质量: 274.20451346
• SMILES: O(c1cc2c(CCN(C(C)C)C(C)C)c[nH]c2cc1)C
• Canonical SMILES: COc1ccc2c(c1)c(CCN(C(C)C)C(C)C)c[nH]2
• InChI: InChI=1S/C17H26N2O/c1-12(2)19(13(3)4)9-8-14-11-18-17-7-6-15(20-5)10-16(14)17/h6-7,10-13,18H,8-9H2,1-5H3
• InChIKey: DNBPMBJFRRVTSJ-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: [2-(5-methoxy-1H-indol-3-yl)ethyl]bis(propan-2-yl)amine
• IUPAC传统名: 5-MeO-DIPT
• 别名: 5-methoxy-N,N-bis(1-methylethyl)-1H-Indole-3-ethanamine; 5-MeO-DIPT; Foxy methoxy; Foxy; 5-Methoxy-N,N-diisopropyltryptamine; Diisopropyl-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine

登记号

• CAS号: 4021-34-5
• PubChem SID: 46506676; 160964708
• PubChem CID: 151182

理论计算性质

JChem

• Acid pKa: 17.440752
• 质子受体: 2
• 质子供体: 1
• LogD (pH = 5.5): 0.19873744
• LogD (pH = 7.4): 0.6141407
• Log P: 3.6911604
• 摩尔折射率: 85.2402 cm^3
• 极化性: 34.30691 Å^3
• 极化表面积: 28.26 Å^2
• 可自由旋转的化学键: 6
• 里宾斯基五规则: true

ALOGPS 2.1

• Log P: 4.35
• LOG S: -3.61
• 溶解度: 6.73e-02 g/l

分子性质

产品相关信息

• 纯度: 98%

详细说明

DrugBank - DB01441

• Drug Groups: illicit; experimental
• Description: 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects.
• Pharmacology: 5-methoxy-diisopropyltryptamine, also known as 5-methoxy-N,N-diisopropyltryptamine, 5-MeO-DiPT, foxy methoxy, or just foxy, is a tryptamine that is used recreationally as a psychedelic. 5-MeO-DiPT is orally active, and dosages between 6–20 mg are commonly reported. Many users note an unpleasant body load accompanies higher dosages. 5-MeO-DiPT is also taken by insufflation, or sometimes it is smoked or injected. Some users also report sound distortion, also noted with the related drug, DiPT.
• Affected Organisms: Humans and other mammals
• Absorption: 5-MeO-DIPT produces effects with an onset of 20 to 30 minutes and with peak effects occurring between 1 to 1.5 hours after administration.
• References: DEA [Link]
• External Links: Wikipedia

参考文献

• DEA Link