sodium 2,5,7,10-tetraoxa-6-aluminaundecan-6-uide

• ChemBase编号: 123399
• 分子式: C6H15AlNaO4
• 平均质量: 201.152208
• 单一同位素质量: 201.06834187
• SMILES: [AlH-](OCCOC)OCCOC.[Na+]
• Canonical SMILES: COCCO[AlH-]OCCOC.[Na+]
• InChI: InChI=1S/2C3H7O2.Al.Na/c2*1-5-3-2-4;;/h2*2-3H2,1H3;;/q2*-1;2*+1
• InChIKey: CKVKLEFDNAHFMO-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: sodium 2,5,7,10-tetraoxa-6-aluminaundecan-6-uide
• IUPAC传统名: sodium 2,5,7,10-tetraoxa-6-aluminaundecan-6-uide
• 别名: 二氢双(2-甲氧乙氧基)铝酸钠; Red-Al® 双(2-甲氧乙氧基)氢化铝钠 溶液; 双(2-甲氧基乙氧基)氢化铝钠; bis(2-methoxyethoxy)aluminum(III) sodium hydride; Synhydrid; Vitride; Red-Al; SBAH; Sodium bis(2-methoxyethoxy)aluminum dihydride; Sodium dihydrido-bis(2-methoxyethoxy)aluminate; Red-Al® sodium bis(2-methoxyethoxy)aluminum hydride solution; Sodium dihydrobis(2-methoxyethoxy)aluminate; Sodium bis(2-methoxyethoxy)aluminum hydride

登记号

• CAS号: 22722-98-1
• EC号: 245-178-2
• MDL号: MFCD00011631
• 默克索引号: 148565
• PubChem SID: 24886202; 24851740; 162217752
• PubChem CID: 16684438; 16689465
• Chemspider ID: 21169529
• 维基百科标题: Red-Al

理论计算性质

• 摩尔折射率: 37.7808 cm^3
• 极化性: 17.50261 Å^3
• 极化表面积: 36.92 Å^2
• 可自由旋转的化学键: 8
• 里宾斯基五规则: true
• 质子受体: 4
• 质子供体: 0
• LogD (pH = 5.5): 0.8518
• LogD (pH = 7.4): 0.8518
• Log P: 0.8518

分子性质

理化性质

• 外观: Transparent crystals
• 闪点: 39 °F; 39.2 °F; 4 °C; 4°C(39°F)
• 密度: 1.02 g/mL at 20 °C; 1.020; 1.036 g/mL at 25 °C
• 蒸汽压: 21 mmHg ( 20 °C)

安全信息

• 保存注意事项: Moisture Sensitive
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C); 易燃性(Flammable) (F); X
• 联合国危险货物编号: 3399; UN3399
• 德国WGK号: 2
• 联合国危险货物等级: 4.3
• 联合国危险货物包装类别(PG): 1; I
• 危险公开号: 11-14/15-34-48/20-63; 11-14/15-34-48/20-63-65-67; 63-11-14/15-34-48/20-65-67
• 安全公开号: 26-36/37/39-43.11-45-62; 7/8-9-16-20-23-26-30-33-36/37/39-43h-...; 9-16-26-36/37/39-43-45
• TSCA收录: 是
• GHS危险品标识: GHS02; GHS05; GHS06; GHS07; GHS08
• GHS警示词: Danger
• 主要危害: Unstable toward water
• 爆炸极限: 7 %
• GHS危险声明: H224-H260-H314-H318-H361-H373-H336; H225-H260-H301 + H311-H304-H315-H318-H336-H361d-H373
• GHS警示性声明: P210-P223-P231 + P232-P261-P370 + P378-P422; P210-P231+P232-P303+P361+P353-P305+P351+P338-P405-P501A
• RID/ADR: UN 3399 4.3/PG 1
• 欧盟补充危害声明: Reacts violently with water.

产品相关信息

• 纯度: 70% w/w in toluene.
• 浓度: ~70% in toluene (~3.5 M); ≥60 wt. % in toluene
• 级别: technical
• 成盐信息: Na+
• 线性分子式: NaAlH2(OCH2CH2OCH3)2

详细说明

Sigma Aldrich - 196193

Application
多功能还原剂。
用于 N-Boc 氨基酸仲酰胺的高效还原，生成手性二胺。1
包装
50, 500 g in Sure/Seal™
法律信息
Red-Al 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 71495

Other Notes
综述1
法律信息
Red-Al 注册商标 Sigma-Aldrich Co. LLC

参考文献

• For use as a superior activator/initiator for the formation of Grignard reagents, see: Coll. Czech. Chem. Commun., 38, 1614 (1973).
• Convenient alternative to lithium aluminum hydride for many reductions: Coll. Czech. Chem. Commun., 34, 118 (1969). The reagent is more readily and safely handled, is more stable to air and can be used at high temperatures. For use in the stereospecific reduction of 2-yn-1-ols to (E)-allylic alcohols, and reviews, see: Org. Synth. Coll., 7, 524 (1990):
  
• The reducing properties can be modified by addition of one mole of ethanol, which gives a reagent for the reduction of lactones to lactols, or one mole of N-methylpiperazine or morpholine, which gives a reagent for the high-yield reduction of esters to aldehydes: Synthesis, 526 (1976).