sodium tetradecanoate

• ChemBase编号: 111180
• 分子式: C14H27NaO2
• 平均质量: 250.35275
• 单一同位素质量: 250.19087439
• SMILES: [Na+].CCCCCCCCCCCCCC(=O)[O-]
• Canonical SMILES: CCCCCCCCCCCCCC(=O)[O-].[Na+]
• InChI: InChI=1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1
• InChIKey: JUQGWKYSEXPRGL-UHFFFAOYSA-M

名称和登记号

名称

• IUPAC标准名: sodium tetradecanoate
• IUPAC传统名: sodium myristate; potassium myristate
• 别名: 十四烷酸 钠盐; 肉豆蔻酸 钠盐; Myristic acid sodium salt; Tetradecanoic acid sodium salt; Sodium myristate; SODIUM MYRISTATE

登记号

• CAS号: 822-12-8
• EC号: 212-487-9
• MDL号: MFCD00042653
• Beilstein号: 3575157
• PubChem SID: 162096564; 24886060; 24897209
• PubChem CID: 23693095

理论计算性质

• Acid pKa: 4.9520197
• 质子受体: 2
• 质子供体: 0
• LogD (pH = 5.5): 4.71164
• LogD (pH = 7.4): 2.9525049
• Log P: 5.3674455
• 摩尔折射率: 78.7187 cm^3
• 极化性: 26.917377 Å^3
• 极化表面积: 40.13 Å^2
• 可自由旋转的化学键: 12
• 里宾斯基五规则: false

分子性质

安全信息

• 德国WGK号: 1
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C

产品相关信息

• 纯度: ≥98.0% (NT); ≥99%
• 线性分子式: CH3(CH2)12COONa

详细说明

MP Biomedicals - 05218067

MP Biomedicals Rare Chemical collection

Sigma Aldrich - M8005

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70140

Application
Sodium myristate was used for the N-myristoylation of recoverin 1.
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.