1-bromo-3-chloropropane

• ChemBase编号: 109499
• 分子式: C3H6BrCl
• 平均质量: 157.43674
• 单一同位素质量: 155.93413987
• SMILES: ClCCCBr
• Canonical SMILES: ClCCCBr
• InChI: InChI=1S/C3H6BrCl/c4-2-1-3-5/h1-3H2
• InChIKey: MFESCIUQSIBMSM-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 1-bromo-3-chloropropane
• IUPAC传统名: 1-chloro-3-bromopropane
• 别名: 1,3-溴氯丙烷; 三亚甲基氯溴化合物; 1-溴-3-氯丙烷; 1-Chloro-3-bromopropane; 3-Bromo-1-chloropropane; 3-Bromopropyl Chloride; 3-Chloro-1-bromopropane; 3-Chloropropan-1-yl Bromide; 3-Chloropropyl Bromide; NSC 9183; Trimethylene Bromide Chloride; ω-Chlorobromopropane; 1-BROMO-3-CHLOROPROPANE; I-BCP; 1-Bromo-3-chloropropane; Trimethylene bromochloride; Trimethylene chlorobromide

登记号

• CAS号: 109-70-6
• EC号: 203-697-1
• MDL号: MFCD00000998
• Beilstein号: 605278
• PubChem SID: 24891900; 24892149; 162095222
• PubChem CID: 8006

理论计算性质

• 质子受体: 0
• 质子供体: 0
• LogD (pH = 5.5): 1.7459596
• LogD (pH = 7.4): 1.7459596
• Log P: 1.7459596
• 摩尔折射率: 28.5045 cm^3
• 极化性: 11.027107 Å^3
• 极化表面积: 0.0 Å^2
• 可自由旋转的化学键: 2
• 里宾斯基五规则: true

分子性质

理化性质

• 熔点: -59°C; -59°C
• 沸点: 142-145°C; 144-145 °C(lit.)
• 闪点: >140°C(284°F); 113 °F; 45 °C
• 密度: 1.592 g/mL at 25 °C(lit.); 1.5969 g/ml; 1.598
• 折射率: 1.4855; n20/D 1.486; n20/D 1.486(lit.)

安全信息

• RTECS编号: TX4113000
• 欧盟危险性物质标志: X; 有害性(Harmful) (Xn)
• 联合国危险货物编号: 2688; UN2688
• 德国WGK号: 3
• 联合国危险货物等级: 6.1
• 联合国危险货物包装类别(PG): 3; III
• 危险公开号: 10-20/22; 20/22-52/53; R:22
• 安全公开号: 16; 9-23-36-61; S:36/37/39
• TSCA收录: 是
• GHS危险品标识: GHS02; GHS06
• GHS警示词: Danger
• GHS危险声明: H226-H302-H331; H331-H302-H402-H412
• GHS警示性声明: P261-P311; P261-P321-P304+P340-P311-P405-P501A
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• RID/ADR: UN 2688 6.1/PG 3

产品相关信息

• 纯度: ≥98.0% (GC); ≥99%; 99%
• 级别: purum
• 线性分子式: Cl(CH2)3Br

详细说明

MP Biomedicals - 05211313

MP Biomedicals Rare Chemical collection

Sigma Aldrich - B9673

Application
BCP can be used in place of chloroform, and is less toxic. The use of BCP in the single-step TRI® Reagent method decreases the possibility of contaminating RNA with DNA. It does not adversely affect quality or quantity of the isolated RNA.
包装
200 mL in glass bottle

Sigma Aldrich - B62404

包装
1 kg in glass bottle
250 g in glass bottle

Toronto Research Chemicals - B682450

1-Bromo-3-chloropropane can be used safer and equally efficient alternative to chloroform as a phase-separation agent in the 1-step method of RNA isolation from biological samples such as animal and plant tissue.

参考文献

• Chomczynski, P. et al.: Anal. Biochem., 225, 163 (1995)
• Chey, S. et al.: Anal. Biochem., 411, 164 (1995)