boric acid

• ChemBase编号: 105578
• 分子式: BH3O3
• 平均质量: 61.83302
• 单一同位素质量: 62.01752436
• SMILES: OB(O)O
• Canonical SMILES: OB(O)O
• InChI: InChI=1S/BH3O3/c2-1(3)4/h2-4H
• InChIKey: KGBXLFKZBHKPEV-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: boric acid
• IUPAC传统名: boric acid
• 别名: 硼酸, Puratronic®; 硼酸, ACS; 硼酸; 硼酸 溶液; 硼原子吸收标准液; 硼酸; 硼原子光谱标准浓缩液 1.000g B; 硼酸 溶液; Boron standard solution; Boric acid, Puratronic®; Boric acid, ACS; Acidum boricum; Boric acid solution; Boron standard for AAS; Boracic Acid; Orthboric Acid; BORIC ACID ACS REAGENT GRADE; BORIC ACID; Boric acid; Orthoboric acid; Sassolite; Optibor; Borofax; Boron atomic spectroscopy standard concentrate 1.000 g B; Boric acid solution; Boron standard solution

登记号

• CAS号: 10043-35-3
• EC号: 233-139-2
• MDL号: MFCD00011337
• Beilstein号: 1697939
• 默克索引号: 141336
• PubChem SID: 24858526; 162092366; 24891517; 24891821; 24891508; 24891666; 24847260; 24892148; 24860608; 24852125; 24891620; 24892029; 24849566; 24849622; 24847262; 24892015
• PubChem CID: 7628
• CHEBI ID: 33118
• CHEMBL: 42403
• Chemspider ID: 7346
• KEGG ID: D01089
• 美国药典/FDA物质标识码: R57ZHV85D4
• 维基百科标题: Boric_acid

理论计算性质

• Acid pKa: 8.698678
• 质子受体: 3
• 质子供体: 3
• LogD (pH = 5.5): -0.5088733
• LogD (pH = 7.4): -0.52978307
• Log P: -0.5086
• 摩尔折射率: 7.6938 cm^3
• 极化性: 4.730119 Å^3
• 极化表面积: 60.69 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 2.52 g/100 mL (0 °C) ; 4.72 g/100 mL (20 °C) ; 5.7 g/100 mL (25 °C) ; 19.10 g/100 mL (80 °C) ; 27.53 g/100 mL (100 °C) in water; ethanol: in accordance; H2O: soluble; H2O: soluble0.5 M, clear, colorless; H2O: soluble1 M, clear, colorless (hot); Soluble in lower alcohols ; moderately soluble in pyridine ; very slightly soluble in acetone; Soluble in water (1 gram in 18ml cold or 4ml boiling water). Solubility in water is increased by addition of HCl, citric or tartaric acid
• 外观: +8 Mesh Granular; APHA: ≤10; granular; Granular; powder; Powder; tablet; White crystalline solid
• 熔点: 160 °C (dec.)(lit.); 168 - 170 °C; 170.9°C; ca 185°C dec.
• 沸点: 300 °C; 300°C
• 闪点: None; Non-flammable.
• 密度: 1.435; 1.435 g/cm^3; 1.5172 g/cm^3 at 14 °C
• 蒸汽压: 2.6 mmHg ( 20 °C)
• 紫外吸收波长: A1M/260, H2O ≤0.05; A1M/280, H2O ≤0.05; λ: 260 nm Amax: 0.015; λ: 280 nm Amax: 0.010
• pKa: 9.24 (see text)
• pH值: 3.5-6.0 (0.5 M in H2O); 3.6-4.0 (20 °C, 4%); 3.6-4.4 (25 °C, saturated solution in H2O); 3.8-4.8 (20 °C, 3.3%)

安全信息

• 保存条件: Room Temperature (15-30°C); Room Temperature (15-30°C), Desiccate
• RTECS编号: ED4550000
• 欧盟危险性物质标志: Harmful (Xn); Repr. Cat. 2; 有毒(Toxic) (T); 刺激性(Irritant) (Xi)
• 德国WGK号: 1; nwg
• 危险公开号: 60-61; R:36/37/38; R60 R61
• 安全公开号: 53-45; S:20-25-26-37/39; S53 S45
• TSCA收录: 是
• GHS危险品标识: GHS08
• GHS警示词: Danger
• NFPA704:
  

  0

  1

  0
• 半数致死量: 2660 mg/kg, oral (rat)
• GHS危险声明: H360; H360-H303
• GHS警示性声明: P201-P308 + P313; P201-P312-P308+P313
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges; Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

产品相关信息

• 纯度: ~99%; ≥99%; ≥99.0% (T); ≥99.5%; ≥99.5% (T); ≥99.5% (titration); ≥99.8%; 4%±0.05%; 98%; 99.5% min; 99.5-100.5%; 99.8%; 99.97% trace metals basis; 99.99% (metals basis); 99.999% trace metals basis; 99.9995% (metals basis); 99+%
• 浓度: 1 mg/mL B; 1.000 g/L B; 1000 ppm B; in H2O
• 级别: ACS; ACS reagent; Biotechnology Performance Certified; for electrophoresis; for ICP; for molecular biology; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; REAGENT; ReagentPlus®; SAJ first grade
• 颗粒大小: 20-230 mesh
• 适用性: cell culture tested; complies for appearance of solution; plant cell culture tested; suitable for amino acid analysis; suitable for atomic absorption spectrometry; suitable for cell culture; suitable for plant cell culture
• 杂质: <0.05% non-volatile substances in MeOH/HCl; ≤0.001% heavy metals (as Pb); ≤0.005% Insoluble in methanol; ≤0.005% insoluble in methanol; ≤0.005% Phosphorus (P); ≤0.05% non-volatile substances in MeOH/HCl; ≤0.05% Nonvolatile with methanol; ≤0.05% with methanol-HCl non-volat. matter; ≤0.1% Insoluble matter; Bioburden, tested; DNases, none detected; endotoxin, tested; insoluble matter, passes filter test; organic substances, complies; phosphatases, none detected; proteases, none detected; residual solvents, complies; RNases, none detected
• 痕量阳离子: Ag: ≤0.05 mg/kg; Al: ≤0.0005%; Al: ≤0.1 mg/kg; Al: ≤5 mg/kg; As: ≤0.5 mg/kg; As: ≤5 mg/kg; Ba: ≤0.05 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.005%; Ca: ≤0.1 mg/kg; Ca: ≤10 mg/kg; Ca: ≤20 mg/kg; Ca: ≤50 mg/kg; Cd: ≤0.05 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Co: ≤0.05 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤0.05 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤0.1 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Fe: ≤0.0005%; Fe: ≤0.001%; Fe: ≤0.05 mg/kg; Fe: ≤1 mg/kg; Fe: ≤5 mg/kg; Fe: ≤5 ppm; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤0.001%; heavy metals (as Pb): ≤10 ppm; K: ≤0.005%; K: ≤100 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.005%; Mg: ≤0.05 mg/kg; Mg: ≤5 mg/kg; Mg: ≤5 ppm; Mn: ≤0.05 mg/kg; Mn: ≤5 mg/kg; Mo: ≤0.05 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.01%; Na: ≤100 mg/kg; Na: ≤50 mg/kg; NH4+: ≤0.05%; Ni: ≤0.1 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤0.1 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sn: ≤0.1 mg/kg; Sr: ≤0.05 mg/kg; Sr: ≤5 mg/kg; Ti: ≤0.05 mg/kg; V: ≤0.05 mg/kg; Zn: ≤0.0005%; Zn: ≤0.05 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg; Zr: ≤0.05 mg/kg
• 痕量阴离子: chloride (Cl-): ≤0.001%; chloride (Cl-): ≤0.05%; chloride (Cl-): ≤3 mg/kg; chloride (Cl-): ≤5 mg/kg; chloride (Cl-): ≤50 mg/kg; phosphate (PO43-): ≤0.001%; phosphate (PO43-): ≤5 mg/kg; sulfate (SO42-): ≤0.01%; sulfate (SO42-): ≤0.05%; sulfate (SO42-): ≤200 mg/kg; sulfate (SO42-): ≤400 mg/kg; sulfate (SO42-): ≤5 mg/kg
• Foreign Activity: DNase, RNase, and protease, none detected; DNase, RNase, Protease, none detected
• 有效期: (limited shelf life, expiry date on the label)
• 干燥失重: ≤0.5% loss on drying, 20 °C (HV); ≤0.5% loss on drying, 5 h (on silica gel)
• 品质说明: ampule; meets analytical specification of Ph. Eur., BP, NF
• λ: 1 M in H2O
• 产品线: BioUltra
• 线性分子式: H3BO3

详细说明

MP Biomedicals - 02194810

Molecular Biology Reagent
Purity: ~99%
Fe: =5 ppm

MP Biomedicals - 02191411

ACS Reagent Grade
Crystalline

Sigma Aldrich - 15663

Other Notes
Running buffer component with methylmercuric hydroxide gels1; Buffer component in DNA digest analysis with capillary electrophoresis2
Application
Boric acid can be used to study molecular biology, DNA and RNA purification, biological buffers and molecular biology reagents. Boric acid has been used to test the toxic effects of boron on growth and antioxidant system parameters of maize (Zea mays L.) roots. Boric acid has also been used to study the effect of time period after boric acid injection on (10)B absorption in different regions of adult male rat′s brain.

Sigma Aldrich - B2645

Quantity
每片含 1g 硼酸。

Sigma Aldrich - 15579

Preparation Note
由 B(OH)3 和 H2O 制备

Sigma Aldrich - 416711

法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 15670

Other Notes
丙二酸酯脱羧的催化剂1

Sigma Aldrich - 15665

Other Notes
Calibration of polyacrylamide gel columns for the separation of oligonucleotides by capillary electrophoresis1

Sigma Aldrich - 202878

包装
10, 50, 250 g in poly bottle

Sigma Aldrich - B0252

包装
1, 2.5 kg in poly bottle
5, 10 kg in poly drum
500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 339067

包装
100, 500 g in poly bottle

Sigma Aldrich - B0394

包装
1 kg in poly bottle
100, 500 g in poly bottle
5, 12 kg in poly drum

参考文献

• Promotes the decarboalkoxylation of malonic esters and analogous compounds: Synth. Commun., 9, 609 (1979); Org. Synth. Coll., 6, 615 (1988); Can. J. Chem., 69, 1201 (1991).
• Catalyzes the N-acylation of indoles with carboxylic acids: Heterocycles, 19, 91 (1982). Promotes the reaction between Benzenesulfinic acid sodium salt, A12118, and propiolate esters, under phase-transfer conditions, to give (Z)-vinyl sulfones: Org. Synth. Coll., 8, 458 (1993).