octadeca-6,9,12-trienoic acid

• ChemBase编号: 104249
• 分子式: C18H30O2
• 平均质量: 278.4296
• 单一同位素质量: 278.2245802
• SMILES: CCCCC/C=C/C/C=C/C/C=C/CCCCC(=O)O
• Canonical SMILES: CCCCC/C=C/C/C=C/C/C=C/CCCCC(=O)O
• InChI: InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)
• InChIKey: VZCCETWTMQHEPK-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: octadeca-6,9,12-trienoic acid
• IUPAC传统名: 6,9,12-octadecatrienoic acid
• 别名: 顺,顺,顺-6,9,12-十八碳三烯酸; γ-亚麻酸; cis,cis,cis-6,9,12-Octadecatrienoic acid; γ-Linolenic acid; 6,9,12-Octadecatrienoic acid; γ-LINOLENIC ACID; Gamma-linolenic acid; gamolenic acid; GLA; Gamma-Linolenic acid

登记号

• CAS号: 506-26-3
• MDL号: MFCD00065718
• Beilstein号: 1712253
• PubChem SID: 24882200; 162091508; 24896312
• PubChem CID: 5280933; 5353640
• CHEBI ID: 28661
• ATC码: D11AX02
• CHEMBL: 464982
• Chemspider ID: 4444436
• 美国药典/FDA物质标识码: 78YC2MAX4O
• 维基百科标题: Gamma-Linolenic_acid

理论计算性质

• Acid pKa: 4.922493
• 质子受体: 2
• 质子供体: 1
• LogD (pH = 5.5): 5.381
• LogD (pH = 7.4): 3.6179216
• Log P: 6.059955
• 摩尔折射率: 89.6354 cm^3
• 极化性: 33.692265 Å^3
• 极化表面积: 37.3 Å^2
• 可自由旋转的化学键: 13
• 里宾斯基五规则: false

分子性质

理化性质

• 外观: Colorless oil; liquid
• 闪点: 110 °C; 230 °F
• 折射率: n20/D 1.471

安全信息

• 保存条件: 0°C
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 3
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• 保存温度: -20°C

产品相关信息

• 纯度: ≥97.0% (GC); ≥99%; ≥99.0% (GC); 99%
• 级别: analytical standard
• 有效期: (limited shelf life, expiry date on the label)
• Empirical Formula (Hill Notation): C18H30O2

详细说明

MP Biomedicals - 02155244

(6,9,12-Octadecatrienoic acid) Purity: 99% Sealed ampule (liquid).

Sigma Aldrich - L2378

包装
10 mg in autosmp vl
Sealed ampule.
Biochem/physiol Actions
γ-Linolenic acid , a polyunsaturated fatty acid, exerts anti-inflammatory effect by decreasing both interleukin (IL) 6 and IL-8 production in the human enterocyte-like cell line Caco-2 and humandendritic cells in vitro 1.

Sigma Aldrich - 62172

Biochem/physiol Actions
γ-Linolenic acid , a polyunsaturated fatty acid, exerts anti-inflammatory effect by decreasing both interleukin (IL) 6 and IL-8 production in the human enterocyte-like cell line Caco-2 and humandendritic cells in vitro 1.

Sigma Aldrich - 62174

Biochem/physiol Actions
γ-Linolenic acid , a polyunsaturated fatty acid, exerts anti-inflammatory effect by decreasing both interleukin (IL) 6 and IL-8 production in the human enterocyte-like cell line Caco-2 and humandendritic cells in vitro 1.