sodium 2-iodoacetate

• ChemBase编号: 103329
• 分子式: C2H2INaO2
• 平均质量: 207.93032
• 单一同位素质量: 207.89972159
• SMILES: [Na+].[O-]C(=O)CI
• Canonical SMILES: [O-]C(=O)CI.[Na+]
• InChI: InChI=1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
• InChIKey: AGDSCTQQXMDDCV-UHFFFAOYSA-M

名称和登记号

名称

• IUPAC标准名: sodium 2-iodoacetate
• IUPAC传统名: potassium 2-iodoacetate; sodium 2-iodoacetate
• 别名: Iodoacetic acid 钠盐; SODIUM IODOACETATE; Sodium iodacetate; IODOACETIC ACID; Iodoacetic acid sodium salt; Sodium iodoacetate

登记号

• CAS号: 305-53-3
• EC号: 206-165-7
• MDL号: MFCD00002686
• Beilstein号: 4009322
• PubChem SID: 24895977; 162091284; 24896151; 24880938
• PubChem CID: 5239

理论计算性质

• Acid pKa: 3.0473845
• 质子受体: 2
• 质子供体: 0
• LogD (pH = 5.5): -1.6969876
• LogD (pH = 7.4): -2.7464745
• Log P: 0.7222152
• 摩尔折射率: 36.5646 cm^3
• 极化性: 10.381431 Å^3
• 极化表面积: 40.13 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble0.5 M, clear, colorless; methanol: soluble0.1 M at 20 °C, clear, colorless
• 熔点: 208 °C (dec.)(lit.); 208°C

安全信息

• 保存条件: 0°C, Desiccate, Store Under Nitrogen
• RTECS编号: AI3675000
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C); 有毒(Toxic) (T)
• 联合国危险货物编号: 2811; 2923
• 德国WGK号: 3
• 联合国危险货物等级: 6.1; 8
• 联合国危险货物包装类别(PG): 3; II
• 澳大利亚Hazchem: 2X
• 危险公开号: 25-37/38-41; R:22-34
• 安全公开号: 26-39-45; S:26-27/28-36/37/39-46-64
• 欧盟危险货物分类: CT2
• 欧盟危险识别号(EUHIN): 8B
• 美国ERG指导号: 154
• GHS危险品标识: GHS05; GHS06
• GHS警示词: Danger
• GHS危险声明: H301-H315-H318-H335
• GHS警示性声明: P261-P280-P301 + P310-P305 + P351 + P338
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• RID/ADR: UN 2811 6.1/PG 3
• 保存温度: -20°C

产品相关信息

• 纯度: ≥98%; ≥98.0% (NT); ≥99.0% (NT); ≥99.5% (NT)
• 级别: purum
• 杂质: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter; ≤0.5% water; insoluble matter, passes filter test
• 痕量阳离子: Al: ≤0.0005%; Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.001%; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.001%; Cu: ≤5 mg/kg; Fe: ≤0.0005%; Fe: ≤5 mg/kg; K: ≤0.02%; K: ≤500 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH4+: ≤0.05%; Ni: ≤5 mg/kg; Pb: ≤0.001%; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤0.0005%; Zn: ≤5 mg/kg
• 痕量阴离子: chloride (Cl-): ≤100 mg/kg; sulfate (SO42-): ≤0.05%; sulfate (SO42-): ≤100 mg/kg
• 产品线: BioUltra
• abs.: absorption0.1M/310 nm, methanol cut-off
• 线性分子式: ICH2COONa

详细说明

MP Biomedicals - 02151348

Sodium Salt
White to light yellow crystals
SH-modifying agent

Sigma Aldrich - 57858

Other Notes
Sulfhydryl reagent1,2
Application
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Sigma Aldrich - I2512

包装
25, 100 g in glass bottle
Application
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.
Biochem/physiol Actions
Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.1

Sigma Aldrich - I9148

Application
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Sigma Aldrich - 57859

Caution
may discolor to yellowish on storage
Other Notes
Sulfhydryl reagent1,2
Application
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Sigma Aldrich - 57860

Caution
may discolor to yellowish on storage
Application
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.