4-[(E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzene-1-sulfonyl chloride

• ChemBase编号: 103206
• 分子式: C14H14ClN3O2S
• 平均质量: 323.79786
• 单一同位素质量: 323.04952538
• SMILES: CN(C)c1ccc(cc1)/N=N/c1ccc(cc1)S(=O)(=O)Cl
• Canonical SMILES: CN(c1ccc(cc1)/N=N/c1ccc(cc1)S(=O)(=O)Cl)C
• InChI: InChI=1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3
• InChIKey: VTVWTPGLLAELLI-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 4-[(E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzene-1-sulfonyl chloride; 4-{2-[4-(dimethylamino)phenyl]diazen-1-yl}benzene-1-sulfonyl chloride
• IUPAC传统名: 4-[(E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzenesulfonyl chloride; 4-{2-[4-(dimethylamino)phenyl]diazen-1-yl}benzenesulfonyl chloride
• 别名: 4-二甲氨基偶氮苯-4'-磺酰氯; 4-(二甲氨基)偶氮苯-4′-磺酰氯; 4-二甲胺基苯基偶氮苯磺酰氯; 4-(二甲氨基)偶氮苯-4′-磺酰氯; 4-(N,N-二甲基氨基)偶氮苯-4'-磺酸氯; 4-二甲胺基苯基偶氮苯磺酰氯; 4-Dimethylaminoazobenzene-4'-sulfonyl chloride; Dabsyl chloride; 4-(4-Dimethylaminophenylazo)benzenesulfonyl chloride; DABS-Cl; 4-DIMETHYLAMINOAZOBENZENE-4'-SULFONYL CHLORIDE; 4-(Dimethylamino)azobenzene-4′-sulfonyl chloride; Dabsyl chloride; 4-(Dimethylamino)azobenzene-4′-sulfonyl chloride

登记号

• CAS号: 56512-49-3
• EC号: 260-235-1
• MDL号: MFCD00007444
• Beilstein号: 3064095
• PubChem SID: 162090350; 24873345; 24864337
• PubChem CID: 91660

理论计算性质

• 质子受体: 5
• 质子供体: 0
• LogD (pH = 5.5): 4.428272
• LogD (pH = 7.4): 4.43342
• Log P: 4.4334865
• 摩尔折射率: 88.9998 cm^3
• 极化性: 32.430676 Å^3
• 极化表面积: 62.1 Å^2
• 可自由旋转的化学键: 4
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: acetonitrile: soluble; DMF: soluble
• 熔点: 185 °C (decomposes); 185 °C (dec.)(lit.); ca 185°C dec.

安全信息

• 保存条件: 2-8°C, Store Under Nitrogen, Protect from light, Avoid excess heat
• 保存注意事项: Moisture Sensitive
• RTECS编号: DB8927800
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• 联合国危险货物编号: 1759; 3261; UN2923
• 德国WGK号: 3
• 联合国危险货物等级: 8
• 联合国危险货物包装类别(PG): 2; II
• 澳大利亚Hazchem: 2X
• 危险公开号: 34; R:34
• 安全公开号: 20-26-36/37/39-45-60; 26-36/37/39-45; S:26-27/28-36/37/39-46-64
• 欧盟危险货物分类: C10
• 欧盟危险识别号(EUHIN): 8B
• 美国ERG指导号: 154
• TSCA收录: 否
• GHS危险品标识: GHS05
• GHS警示词: Danger
• GHS危险声明: H314; H314-H318
• GHS警示性声明: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A; P280-P305 + P351 + P338-P310
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• RID/ADR: UN 3261 8/PG 2

产品相关信息

• 纯度: ≥97.5% (AT); 96%; 98+%
• 级别: for HPLC derivatization
• 包装: pkg of 500 mg
• 线性分子式: (CH3)2NC6H4N=NC6H4SO2Cl

详细说明

MP Biomedicals - 02150931

Chromophoric label for amino acids, peptides and proteins.

Sigma Aldrich - 226262

Application
Chromophoric labeling reagent for amino acids.1,2,3

Sigma Aldrich - 39068

Application
For the qualitative and quantitative identification of amino acids and for the determination of N-terminal amino acids.1,2,3 Used in the determination of primary and secondary amines by HPLC.4
包装
1, 5 g in glass bottle
250 mg in glass bottle

Sigma Aldrich - 502219

General description
HPLC 衍生化试剂 丹磺酰氯(4-二甲胺基-偶氮苯-4-磺酰氯) 在 HPLC 中用于柱前衍生化氨基酸的试剂丹磺酰氨基酸可通过反相 HPLC 进行分离，并在可见光区中被检出。

参考文献

• J.K. Lin, Anal. Chem. , 52 : 630 (1980).
• J.Y. Chang, et al., J. Chromatogr., 116 : 215 (1976).
• J.K. Lin, et al., Anal. Chem., 47: 1634 (1975).
• Reagent for the qualitative and quantitative estimation of amino acids: Anal. Chem., 47, 1634 (1975); 52, 630 (1980); J. Chromat., 116, 215 (1976).