4-(3,4-diaminophenyl)benzene-1,2-diamine tetrahydrochloride

• ChemBase编号: 103175
• 分子式: C12H18Cl4N4
• 平均质量: 360.11012
• 单一同位素质量: 358.02855732
• SMILES: Cl.Cl.Cl.Cl.Nc1ccc(cc1N)c1ccc(N)c(N)c1
• Canonical SMILES: Nc1ccc(cc1N)c1ccc(c(c1)N)N.Cl.Cl.Cl.Cl
• InChI: InChI=1S/C12H14N4.4ClH/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8;;;;/h1-6H,13-16H2;4*1H
• InChIKey: KJDSORYAHBAGPP-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 4-(3,4-diaminophenyl)benzene-1,2-diamine tetrahydrochloride
• IUPAC传统名: 3,3'-diaminobenzidine tetrahydrochloride
• 别名: 3,3′,4,4′-四氨基联苯 四盐酸盐; 3,3′-Diaminobenzidine tetrahydrochloride; 3,3′-Diaminobenzidine tetrahydrochloride; 3,3′,4,4′-Biphenyltetramine tetrahydrochloride; DAB; 3,3'-Diaminobenzidine Tetrahydrochloride; 3,3',4,4'-Tetraaminobiphenyl Tetrahydrochloride; 3,3'-DIAMINOBENZIDINE TETRAHYDROCHLORIDE; 3,3′-Diaminobenzidine (DAB) Liquid Substrate Dropper System; 3,3′-Diaminobenzidine (DAB) Enhanced Liquid Substrate System tetrahydrochloride; 3,3′,4,4′-Tetraaminobiphenyl tetrahydrochloride; 3,3',4,4'-BiphenyltetraMine tetrahydrochloride; 4-(3,4-diaminophenyl)benzene-1,2-diamine tetrahydrochloride

登记号

• CAS号: 7411-49-6
• EC号: 231-018-9
• MDL号: MFCD00012969
• Beilstein号: 1212988
• PubChem SID: 24894054; 162091251; 24894154; 24893801; 24893981
• PubChem CID: 23892

理论计算性质

• 质子受体: 4
• 质子供体: 4
• LogD (pH = 5.5): 0.23196726
• LogD (pH = 7.4): 0.3037893
• Log P: 0.30476737
• 摩尔折射率: 69.9958 cm^3
• 极化性: 25.874 Å^3
• 极化表面积: 104.08 Å^2
• 可自由旋转的化学键: 1
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: liquid; tablet; tablets
• 熔点: > 300°C; 175 - 177°C
• 疏水性(logP): 0.0

安全信息

• 保存条件: 0°C
• RTECS编号: DV8753000
• 欧盟危险性物质标志: 易燃性(Flammable) (F); 有毒(Toxic) (T)
• 联合国危险货物编号: 1230
• 德国WGK号: 3
• 联合国危险货物等级: 9
• 联合国危险货物包装类别(PG): 2
• 危险公开号: 23/24/25-36/38-39/23/24/25; 45-68; R:40
• 安全公开号: 53-45; 7-16-24-33-36/37-45; S:28-36/37/39-45-53
• GHS危险品标识: GHS08
• GHS警示词: Danger
• GHS危险声明: H341-H350
• GHS警示性声明: P201-P281-P308 + P313
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RID/ADR: UN 1230 9/PG 2
• 保存温度: -20°C; 2-8°C

产品相关信息

• 纯度: 95%; 97%; 97.0-103.0%
• 级别: for biological purposes
• 包装: set of 50 tablets
• 运输包装: wet ice
• 线性分子式: (NH2)2C6H3C6H3(NH2)2 · 4HCl

详细说明

MP Biomedicals - 02150825

Color: white to pink
Reagent used in colorimetric analysis of Se and other metals.

MP Biomedicals - 02150826

Tetrahydrochloride
Available in Ready-to-Use preweighed serum vials. Buffer may be directly injected with a hypodermic syringe without exposing the contents of the vial to the atmosphere.

Sigma Aldrich - D3939

Application
The DAB (3,3′-Diaminobenzidine tetrahydrochloride) Two-component Enhanced Liquid Substrate System is a precipitating substrate system for peroxidase. DAB Two-component Liquid Substrate System produces a brown precipitate for use in immunohistological and immunoblotting staining procedures.
Caution
Stable for up to 18 mo. when stored at 2-8 °C in the original container.
Quantity
Each DAB Two-component Liquid Substrate System will provide 100 mL of the DAB substrate solution.

Sigma Aldrich - D6815

Application
The DAB (3,3′-Diaminobenzidine tetrahydrochloride) Two-component Enhanced Liquid Substrate System is a precipitating substrate system for peroxidase. DAB Two-component Liquid Substrate System produces a brown precipitate for use in immunohistological and immunoblotting staining procedures.
Caution
Stable for up to 18 mo. when stored at 2-8 °C in the original container.
包装
Set consists of 4 x 100 ml Solution A and 15 ml Solution B.
Quantity
Each DAB Two-component Liquid Substrate System will provide 500 mL of the DAB substrate solution.

Sigma Aldrich - D5905

Application
Reagent for spectrophotometric determination of selenium.
Reconstitution
Dissolve 1 tablet in 15 ml of Tris-buffered saline, pH 7.6. Add 12 μl of fresh 30% hydrogen peroxide. DAB and hydrogen peroxide concentration may be adjusted to suit individual applications.
Specificity
Peroxidase substrate suitable for use in immunoblotting and immunohistological staining procedures. This substrate produces an insoluble end product that is brown in color and can be observed visually.

Sigma Aldrich - D7679

Application
DAB (3,3′-Diaminobenzidine Tetrahydrochloride) Liquid Substrate Dropper System is a precipitating substrate system for peroxidase. The DAB liquid substrate dropper system has been developed for use in immunohistological staining of tissue sections fixed to slides.
Caution
Stable at least one year at 2-8 °C.
Quantity
Each DAB liquid substrate dropper system will provide ten individual application dropper bottles of 10 mL of a fast and convenient DAB substrate solution.
General description
DAB (3,3′-Diaminobenzidine Tetrahydrochloride) Liquid Substrate Dropper System has been developed for use in immunohistology and immunoblotting procedures as a precipitating substrate for the detection of peroxidase activity. DAB is the immunohistology substrate of choice because it produces an intense brown stain that is easily observed. The end product is resistant to alcohol, therefore, a variety of counterstains and mounting media can be used with the DAB Liquid Substrate Dropper System. DAB Liquid Substrate Dropper System provides all of the chromogen and buffer/peroxide solutions needed to produce a fast and convenient DAB substrate solution.

Sigma Aldrich - 32748

Application
Reagent for spectrophotometric determination of selenium.
Specificity
Peroxidase substrate suitable for use in immunoblotting and immunohistological staining procedures. This substrate produces an insoluble end product that is brown in color and can be observed visually.

Sigma Aldrich - 07-0850

Application
Reagent for spectrophotometric determination of selenium.
Specificity
Peroxidase substrate suitable for use in immunoblotting and immunohistological staining procedures. This substrate produces an insoluble end product that is brown in color and can be observed visually.
Suitability
for biological purposes

参考文献

• Anal. Chem., 30: 1370 (1958).