2-amino-2-methylpropane-1,3-diol

• ChemBase编号: 103012
• 分子式: C4H11NO2
• 平均质量: 105.13564
• 单一同位素质量: 105.0789786
• SMILES: CC(N)(CO)CO
• Canonical SMILES: OCC(CO)(N)C
• InChI: InChI=1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3
• InChIKey: UXFQFBNBSPQBJW-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 2-amino-2-methylpropane-1,3-diol
• IUPAC传统名: AMPD
• 别名: 氨甲基丙二醇; 2-氨基-2-甲基-1,3-丙二醇; Ammediol; 2-Amino-2-methyl-1,3-propanediol; 2-amino-2-methylpropane-1,3-diol; Isobutanediol-2-amine; Aminoglycol; AMPD; Gentimon; Pentaerythritol dichlorohydrin; 2-AMINO-2-METHYL-1,3-PROPANEDIOL

登记号

• CAS号: 115-69-5
• EC号: 204-100-7
• MDL号: MFCD00004678
• Beilstein号: 635708
• PubChem SID: 162090219; 24891493; 24846196; 24891223; 24846197
• PubChem CID: 1531

理论计算性质

• Acid pKa: 14.420516
• 质子受体: 3
• 质子供体: 3
• LogD (pH = 5.5): -4.65181
• LogD (pH = 7.4): -3.7015345
• Log P: -1.6653192
• 摩尔折射率: 26.8118 cm^3
• 极化性: 10.888223 Å^3
• 极化表面积: 66.48 Å^2
• 可自由旋转的化学键: 2
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble0.5 M at 20 °C, clear, colorless; H2O: soluble1 M at 20 °C, clear, colorless
• 熔点: 100-110 °C; 100-110 °C(lit.); 108 - 110°C; 109-111°C
• 沸点: 151 °C/10 mmHg(lit.); 151°C (dec.)
• 蒸汽压: ~10 mmHg ( 152 °C)
• 蒸汽密度: 3.63 (vs air)
• 紫外吸收波长: λ: 260 nm Amax: 0.05; λ: 280 nm Amax: 0.03
• 疏水性(logP): -1.091
• pKa: 8.8 (25°C)
• pH值: 10.0-12.0 (20 °C, 0.5 M in H2O); 10.5-11.5 (25 °C, 1 M in H2O)

安全信息

• 保存条件: Room Temperature (15-30°C)
• RTECS编号: TY2975000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 联合国危险货物编号: 3259
• 德国WGK号: 1
• 联合国危险货物等级: 8
• 联合国危险货物包装类别(PG): 2
• 危险公开号: 36/37/38; R:36/37/38
• 安全公开号: 26-36; S:20-25-26-37/39
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• RID/ADR: UN 3259 8/PG 2

产品相关信息

• 纯度: ≥97.0% (GC); ≥99%; ≥99.5% (NT); 95%; 99%
• 燃烧残渣: <0.1%
• 杂质: <0.005% Phosphorus (P); <0.1% Insoluble matter; insoluble matter, passes filter test
• 痕量阳离子: Al: <0.001%; Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: <0.0005%; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: <0.0005%; Cu: ≤5 mg/kg; Fe: <0.0005%; Fe: ≤5 mg/kg; K: <0.005%; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: <0.0005%; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: <0.005%; Na: ≤50 mg/kg; NH4+: <0.05%; Ni: ≤5 mg/kg; Pb: <0.001%; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: <0.0005%; Zn: ≤5 mg/kg
• 痕量阴离子: carbonate (CO32-): ≤1000 mg/kg; chloride (Cl-): <0.05%; chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): <0.05%; sulfate (SO42-): ≤50 mg/kg
• 干燥失重: ~1% loss on drying
• 产品质量级别: PREMIUM
• λ: 1 M in H2O
• 适用pH范围: 7.8 - 9.7
• 产品线: BioUltra; BioXtra
• 线性分子式: (HOCH2)2C(NH2)CH3

详细说明

MP Biomedicals - 02150354

Crystalline
Biological buffer

Sigma Aldrich - A9754

Application
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.1 Used as a spacer in isotachophoresis of proteins.2,3 Also used as a buffer for the determination of alkaline phosphatase activity.4

Sigma Aldrich - A9074

Application
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.1 Used as a spacer in isotachophoresis of proteins.2,3 Also used as a buffer for the determination of alkaline phosphatase activity.4

Sigma Aldrich - A65174

Application
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.1 Used as a spacer in isotachophoresis of proteins.2,3 Also used as a buffer for the determination of alkaline phosphatase activity.4

Sigma Aldrich - 08569

Application
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.1 Used as a spacer in isotachophoresis of proteins.2,3 Also used as a buffer for the determination of alkaline phosphatase activity.4
2-Amino-2-methyl-1,3-propanediol can be used to study biological buffers. 2-Amino-2-methyl-1,3-propanediol has been used in a study to afford a new family of isostructural octanuclear Cu4Ln4 complexes. 2-Amino-2-methyl-1,3-propanediol has also been used in a study to improve cooling refrigerants for low-temperature applications.

Sigma Aldrich - 08570

Application
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.1 Used as a spacer in isotachophoresis of proteins.2,3 Also used as a buffer for the determination of alkaline phosphatase activity.4