您当前所在的位置:首页 > 产品中心 > 产品详细信息
127-47-9 分子结构
点击图片或这里关闭

3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate

ChemBase编号:102843
分子式:C22H32O2
平均质量:328.48828
单一同位素质量:328.24023026
SMILES和InChIs

SMILES:
CC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C
Canonical SMILES:
CC(=O)OC/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
InChI:
InChI=1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3
InChIKey:
QGNJRVVDBSJHIZ-UHFFFAOYSA-N

引用这个纪录

CBID:102843 http://www.chembase.cn/molecule-102843.html

Collapse All Expand All

名称和登记号

名称和登记号

名称 登记号
IUPAC标准名
3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
IUPAC传统名
3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
vitamin A acetate
别名
乙酸维生素A, 在凝胶中, 粉末, 500,000 I.U./g
维生素 A 醋酸酯
视黄醇乙酸酯
醋酸维生素 A
维生素 A 乙酸酯
视黄醇乙酸酯
Vitamin A acetate in gelatin, 500,000 I.U./g
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-4,6,8-nonatetraen-1-ol Acetate
Vitamin A1 Acetate
all-trans-Retinol Acetate
Retinyl acetate
Retinol acetate
VITAMIN A ACETATE
Vitamin A1 acetate
Acetylretinol
all-trans-Retinol acetate
all-trans-Retinyl acetate
all-trans-Vitamin A acetate;
Retinyl acetate
Vitamin A (acetate)
Retinyl acetate
Vitamin A acetate
trans-Retinol Acetate
trans-RETINYL ACETATE
CAS号
127-47-9
EC号
204-844-2
MDL号
MFCD00019413
Beilstein号
1915439
默克索引号
1410013
PubChem SID
24899359
24899401
24890098
24899372
162090091
24890097
24870469
PubChem CID
638034
Chemspider ID
553599
维基百科标题
Retinyl_acetate

理论计算性质

理论计算性质

JChem
质子受体 质子供体
LogD (pH = 5.5) 5.1352186  LogD (pH = 7.4) 5.1352186 
Log P 5.1352186  摩尔折射率 107.0749 cm3
极化性 40.131332 Å3 极化表面积 26.3 Å2
可自由旋转的化学键 里宾斯基五规则 false 

分子性质

分子性质

理化性质 安全信息 药理学性质 产品相关信息 生物活性(PubChem)
溶解度
absolute ethanol: soluble25 mg/mL (lit.) expand 查看数据来源
Chloroform expand 查看数据来源
Dichloromethane expand 查看数据来源
Ether expand 查看数据来源
Ethyl Acetate expand 查看数据来源
外观
crystalline solid or supercooled liquid expand 查看数据来源
matrix dispersion expand 查看数据来源
Pale Yellow Solid expand 查看数据来源
solid or viscous liquid expand 查看数据来源
熔点
~58 °C(lit.) expand 查看数据来源
57 - 58°C expand 查看数据来源
57-58 °C expand 查看数据来源
57-58°C expand 查看数据来源
保存条件
0°C, Store Under Nitrogen expand 查看数据来源
-20°C Freezer expand 查看数据来源
2-8°C expand 查看数据来源
保存注意事项
Light & Air Sensitive & Hygroscopic expand 查看数据来源
RTECS编号
VH6825000 expand 查看数据来源
欧盟危险性物质标志
X expand 查看数据来源
有害性(Harmful) 有害性(Harmful) (Xn) expand 查看数据来源
MSDS下载
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
德国WGK号
2 expand 查看数据来源
3 expand 查看数据来源
危险公开号
63 expand 查看数据来源
63-38 expand 查看数据来源
R38-R63 expand 查看数据来源
安全公开号
36/37 expand 查看数据来源
S36/37 expand 查看数据来源
TSCA收录
expand 查看数据来源
GHS危险品标识
GHS07 expand 查看数据来源
GHS08 expand 查看数据来源
GHS警示词
Warning expand 查看数据来源
NFPA704
NFPA 704 diagram
1
1
0
expand 查看数据来源
GHS危险声明
H315-H361 expand 查看数据来源
H361 expand 查看数据来源
GHS警示性声明
P281 expand 查看数据来源
P281-P201-P202-P308+P313-P405-P501A expand 查看数据来源
个人保护装置
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter expand 查看数据来源
保存温度
-20°C expand 查看数据来源
2-8°C expand 查看数据来源
作用靶点
Others expand 查看数据来源
纯度
~95% all-trans-isomer basis expand 查看数据来源
级别
analytical standard expand 查看数据来源
成盐信息
Free Base expand 查看数据来源
药效
~2,800,000 I.U. per g expand 查看数据来源
2,600,000-2,940,000 I.U. per g expand 查看数据来源
质检报告
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
下载链接 expand 查看数据来源
包装
ampule of 100 mg expand 查看数据来源
适用性
meets USP testing specifications expand 查看数据来源
suitable for cell culture expand 查看数据来源
杂质
~5% 13-cis-isomer expand 查看数据来源
其他组分
DL-α-tocopherol as stabilizer expand 查看数据来源
生物来源
synthetic expand 查看数据来源
品质说明
concentrate (~50% (w/w) in peanut oil) expand 查看数据来源
特征
standard type fat soluble vitamin expand 查看数据来源
Empirical Formula (Hill Notation)
C22H32O2 expand 查看数据来源

详细说明

详细说明

MP Biomedicals MP Biomedicals Wikipedia Wikipedia Sigma Aldrich Sigma Aldrich TRC TRC
MP Biomedicals -  02103257 external link
Dry: 500,000 IU/g
MP Biomedicals -  02190652 external link
Crystalline
Sigma Aldrich -  95140 external link
Caution
crystallized product can be liquidified by heating to 65°C
Other Notes
isomeric purity: ~95% all-trans- and ~5% 13-cis-isomer
Review: Systematic mode of action of vitamin A1
Unit Definition
1 U corresponds to 1 international unit acc. to Ph Eur II, 217 (1983)
Physical form
may partially crystallize
Biochem/physiol Actions
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.
Sigma Aldrich -  R4632 external link
Analysis Note
Activity based on HPLC comparison to USP standard.
Physical form
Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid
Biochem/physiol Actions
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.
Sigma Aldrich -  R7882 external link
Other Notes
All trans
Preparation Note
The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.
General description
Retinyl-acetate (aka Vitamin A) is found in classical media formulations such as M-199; NCTC-109 and William’s Medium E. Vitamin A is a component of serum use to supplement classical media, consequently most serum containing cell culture systems receive some level of vitamin A. The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells.
Sigma Aldrich -  R3250 external link
Analysis Note
Activity based on HPLC comparison to USP standard.
Physical form
Dispersion in cornstarch-gelatin matrix. Oil dispersible
Biochem/physiol Actions
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.
Sigma Aldrich -  95139 external link
Unit Definition
1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)
Physical form
cristalline solid or supercooled viscous liquid
Sigma Aldrich -  V7763 external link
Physical form
分布于含蔗糖、食物淀粉、尼泊金甲酯、尼泊金丙酯和山梨酸钾防腐剂的明胶基质中。
Toronto Research Chemicals -  V676000 external link
Essential micronutrient.

参考文献

参考文献

供应商提供 Google Scholar IconGoogle Scholar PubMed iconPubMed Google Books IconGoogle Books
  • Heilbron, M., et al.: Biochem. J., 26, 1194 (1932)
  • Kamm, J.J., et al.: J. Am Acad. Dermatol., 6, 652 (1932)
  • Gerster, H., et al.: Int. J. Vitamin. Nutr. Res., 67, 71 (1932)
  • Harrison, E.H., et al.: Annu. Rev. Nutr., 18, 259 (1932)
正在搜索,请耐心等待...(如果遇到网页错误或者长时间没有结果,请刷新页面[F5])

专利

专利

PubChem iconPubChem Patent Google Patent Search IconGoogle Patent

互联网资源

互联网资源

百度图标百度 google iconGoogle