(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid hydrochloride

• ChemBase编号: 102827
• 分子式: C9H12ClNO3
• 平均质量: 217.64948
• 单一同位素质量: 217.05057093
• SMILES: Cl.N[C@@H](Cc1ccc(O)cc1)C(=O)O
• Canonical SMILES: OC(=O)[C@H](Cc1ccc(cc1)O)N.Cl
• InChI: InChI=1S/C9H11NO3.ClH/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;/h1-4,8,11H,5,10H2,(H,12,13);1H/t8-;/m0./s1
• InChIKey: JJWFIVDAMOFNPS-QRPNPIFTSA-N

名称和登记号

名称

• IUPAC标准名: (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid hydrochloride
• IUPAC传统名: L-tyrosine hydrochloride
• 别名: 3-(4-羟基苯基)-L-丙氨酸; L-苯酚氨基丙酸 盐酸盐; L-酪氨酸 盐酸盐; L-TYROSINE HYDROCHLORIDE; L-Tyrosine hydrochloride; 3-(4-Hydroxyphenyl)-L-alanine hydrochloride; 3-(4-Hydroxyphenyl)-L-alanine

登记号

• CAS号: 16870-43-2
• MDL号: MFCD00012617
• PubChem SID: 162090089; 24900004; 24900008
• PubChem CID: 12209702

理论计算性质

• Acid pKa: 1.9998473
• 质子受体: 4
• 质子供体: 3
• LogD (pH = 5.5): -1.4884841
• LogD (pH = 7.4): -1.495157
• Log P: -1.488594
• 摩尔折射率: 47.0972 cm^3
• 极化性: 18.512522 Å^3
• 极化表面积: 83.55 Å^2
• 可自由旋转的化学键: 3
• 里宾斯基五规则: true

分子性质

理化性质

• 熔点: 239 °C (dec.)(lit.); 239°C (dec.)
• 比旋光度: [α]20/D -8°, c = 4 in 1 M HCl

安全信息

• 保存条件: 0°C; Room Temperature (15-30°C)
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 德国WGK号: 3
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves

药理学性质

• 相关基因信息: human ... GRIN2C(2905)mouse ... GRIN2C(14813)rat ... GRIN2C(24411)

产品相关信息

• 纯度: ≥98% (TLC); 99%
• 适用性: suitable for cell culture
• 线性分子式: HOC6H4CH2CH(NH2)CO2H·HCl

详细说明

MP Biomedicals - 02103192

Hydrochloride
Crystalline

MP Biomedicals - 02194760

Cell Culture Reagent
Hydrochloride
Crystalline

Sigma Aldrich - T2025

Other Notes
多巴胺和其他儿茶酚胺的氨基酸前体
General description
Tyrosine is a polar, non-essential amino acid with a phenolic functionality. L-tyrosine is a natural amino acid that is incorporated into proteins as directed by the genetic code. The phenolic function makes the tyrosine residue in proteins a principle recipient of reactions such as phosphorylation/dephosphorylation important for cell signalling. Tyrosine is also a precursor of various neurotransmitters and hormones.

Sigma Aldrich - T2006

Other Notes
多巴胺和其他儿茶酚胺的氨基酸前体
包装
1, 5, 10 g in poly bottle

Sigma Aldrich - 287369

Other Notes
多巴胺和其他儿茶酚胺的氨基酸前体