disodium selenite

• ChemBase编号: 102752
• 分子式: Na2O3Se
• 平均质量: 172.93774
• 单一同位素质量: 173.88080342
• SMILES: [Na+].[Na+].[O-][Se](=O)[O-]
• Canonical SMILES: [O-][Se](=O)[O-].[Na+].[Na+]
• InChI: InChI=1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
• InChIKey: BVTBRVFYZUCAKH-UHFFFAOYSA-L

名称和登记号

名称

• IUPAC标准名: disodium selenite
• IUPAC传统名: disodium selenite; dipotassium selenit
• 别名: 无水亚硒酸钠; 亚硒酸钠; SODIUM SELENITE, ANHYDROUS; Selenious Acid Disodium Salt; Disodium selenite; Natriumselenit; SODIUM SELENITE; Sodium selenite, anhydrous; Sodium selenite; Selenious Acid, Disodium; Selenious acid, disodium salt; SODIUM SELENITE, γ-IRRADIATED

登记号

• CAS号: 10102-18-8
• EC号: 233-267-9
• MDL号: MFCD00003489
• 默克索引号: 148673
• PubChem SID: 24852838; 162090070; 24899643; 24899827
• PubChem CID: 24934
• CHEBI ID: 48843
• ATC码: A12CE02
• CHEMBL: 112302
• Chemspider ID: 23308
• 美国药典/FDA物质标识码: HIW548RQ3W
• 维基百科标题: Sodium_selenite

理论计算性质

• Acid pKa: 1.19897
• 质子受体: 4
• 质子供体: 0
• LogD (pH = 5.5): -3.5574248
• LogD (pH = 7.4): -4.2274547
• Log P: -1.2765
• 摩尔折射率: 17.4436 cm^3
• 极化性: 3.671146 Å^3
• 极化表面积: 63.19 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: 85 g/100 mL (20 °C) in water; Freely soluble in water. Insoluble in alcohol; insoluble in alcohol, ethanol
• 外观: colourless solid; lyophilized powder; powder; Powder
• 熔点: >350 °C(lit.); >350°C; 217 deg. C; 710 °C (decomp.)
• 沸点: 684 +/- 1 deg. C
• 密度: 3.1 g/cm^3
• 蒸汽压: > 0.001 mm Hg at 20 °C

安全信息

• 保存条件: Room Temperature (15-30°C)
• 保存注意事项: Hygroscopic
• RTECS编号: VS7350000
• 欧盟危险性物质标志: Dangerous for the environment (N); 环境危害性(Nature polluting) (N); 剧毒(Highly toxic) (T+); Very toxic (T+)
• 联合国危险货物编号: 2630; UN2630
• 德国WGK号: 2
• 联合国危险货物等级: 6.1
• 联合国危险货物包装类别(PG): 1; I
• 澳大利亚Hazchem: 2X
• 危险公开号: 23-28-31-43-51/53; R:23/24-28-33; R23, R28, R31, R43, R51/53
• 安全公开号: 28-36/37-45-61; S:28-45-20/21; S1/2, S28, S36/37, S45, S61
• 欧盟危险货物分类: T5
• 欧盟危险识别号(EUHIN): 6.1B
• 美国ERG指导号: 151
• TSCA收录: 是
• 欧盟危险品索引: 034-003-00-3
• GHS危险品标识: GHS06; GHS09
• GHS警示词: Danger
• NFPA704:
  

  0

  3

  0
• GHS危险声明: H300-H317-H331-H411; H300-H331-H317-H411
• GHS警示性声明: P261-P264-P273-P280-P301 + P310-P311; P261-P301+P310-P302+P352-P321-P405-P501A
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges; Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• RID/ADR: UN 2630 6.1/PG 1
• 欧盟补充危害声明: Contact with acids liberates toxic gas.

产品相关信息

• 纯度: ~98%; ≥90.0%; ≥95.0% (RT); ≥97.0%; ≥98%; 99%; 99% min, typically 99.75% min (metals basis)
• 级别: JIS special grade; SAJ first grade
• 适用性: suitable for cell culture
• 无菌消毒: γ-irradiated
• 干燥失重: ≤0.5% loss on drying, 200 °C
• 产品质量级别: PREMIUM
• 产品线: BioReagent; BioXtra
• 线性分子式: Na2SeO3

详细说明

MP Biomedicals - 02194741

Cell Culture Reagent
Purity: ~98%

MP Biomedicals - 05201657

MP Biomedicals Rare Chemical collection

MP Biomedicals - 02194587

Cell Culture Reagent
γ-Irradiated
Purity: ~98%

MP Biomedicals - 02102928

White to off-white powder.
Purity: ~98%

Sigma Aldrich - S5261

Application
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Sigma Aldrich - 214485

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
More potent than selenomethionine in reducing carcinogenesis.
包装
100, 500 g in poly bottle
5 g in glass bottle

Sigma Aldrich - 71950

包装
100, 500 g in poly bottle