octadeca-9,12-dienoic acid

• ChemBase编号: 102244
• 分子式: C18H32O2
• 平均质量: 280.44548
• 单一同位素质量: 280.24023026
• SMILES: CCCCC/C=C/C/C=C/CCCCCCCC(=O)O
• Canonical SMILES: CCCCC/C=C/C/C=C/CCCCCCCC(=O)O
• InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)
• InChIKey: OYHQOLUKZRVURQ-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: octadeca-9,12-dienoic acid; (9E,12E)-octadeca-9,12-dienoic acid
• IUPAC传统名: 9,12-octadecadienoic acid; linoelaidic acid
• 别名: 反-9,反-12-十八碳二烯酸; 反亚油酸; 反亚油酸 溶液; 顺-9,顺-12-十八碳二烯酸; 亚油酸; trans-9,trans-12-Octadecadiensäure; Linolelaidic acid; cis-9-cis-12-Octadecadienoic acid; LINOLEIC ACID; 9,12-Octadecadienoic Acid; Leinoleic Acid; 9,12-Linoleic Acid; LINOLEIC ACID FREE ACID; trans-9,trans-12-Octadecadienoic acid; LINOELAIDIC ACID; trans ; trans-9,12-octadecadienoic acid; (9E,12E)-octadeca-9,12-dienoic acid; trans-9,trans-12-Octadecadienoic acid solution; Linoelaidic acid solution; Linolelaidic acid solution; 9-cis,12-cis-Linoleic acid; Telfairic acid; cis-9,cis-12-Octadecadienoic acid; Linoleic acid

登记号

• CAS号: 60-33-3; 506-21-8
• EC号: 200-470-9
• MDL号: MFCD00004435; MFCD00064241
• Beilstein号: 2210856; 1727101
• PubChem SID: 24896270; 162088642; 24901678; 24896275; 24896279; 24882205; 24882204
• PubChem CID: 5282457
• CHEMBL: 93204
• Chemspider ID: 4445609
• FEMA编号: 3380
• 维基百科标题: Linoelaidic_acid
• 欧洲委员会编号: 694
• Flavis Number: 8.041

理论计算性质

• Acid pKa: 4.9881673
• 质子受体: 2
• 质子供体: 1
• LogD (pH = 5.5): 5.7939434
• LogD (pH = 7.4): 4.040287
• Log P: 6.421877
• 摩尔折射率: 88.5188 cm^3
• 极化性: 33.928547 Å^3
• 极化表面积: 37.3 Å^2
• 可自由旋转的化学键: 14
• 里宾斯基五规则: false

分子性质

理化性质

• 溶解度: ethanol: soluble; NaOH: soluble1 M
• 外观: liquid
• 熔点: -5 °C (23 °F); -12 °C (10 °F); -5 °C; -5 °C(lit.)
• 沸点: 229-230 °C (444-446 °F); 229-230 °C at 16 mmHg; 229-230 °C/16 mmHg(lit.)
• 闪点: >113 °C; >235.4 °F; 14 °C; 57.2 °F
• 密度: 0.89 g/ml; 0.89 g/mL at 25 °C(lit.); 0.902 g/mL at 25 °C(lit.); 0.9022 (water = 1)
• 折射率: n20/D 1.466; n20/D 1.466(lit.); n20/D 1.469; n20/D 1.470
• 蒸汽压: Very low at 25 °C, 16 mm Hg (2.13 kPa) at 229 °C

安全信息

• 保存条件: 0°C; 0°C, Store Under Nitrogen
• RTECS编号: RF9990000
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• 德国WGK号: 1; 3
• 危险公开号: 11
• 安全公开号: 16
• GHS危险品标识: GHS02
• GHS警示词: Danger
• GHS危险声明: H225
• GHS警示性声明: P210
• 个人保护装置: Eyeshields, Gloves; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• 保存温度: -20°C; 2-8°C

药理学性质

• 相关基因信息: human ... SOAT1(6646), SOAT2(8435)
• 过敏源: no known allergens

产品相关信息

• 纯度: ~60%; ~65%; ≥85% (GC); ≥93% (GC); ≥98.0% (GC); ≥98.0% (HPLC); ≥98.5% (GC); ≥99%; 60-74% (GC); 95-99%; 99%
• 浓度: ~250 mg/mL in ethanol
• 级别: analytical standard; NI; technical
• 适用性: suitable for cell culture
• 杂质: 18-32% oleic acid
• 有效期: (limited shelf life, expiry date on the label)
• 品质说明: natural
• 产品线: BioReagent
• 线性分子式: CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
• Empirical Formula (Hill Notation): C18H32O2
• 分类: Derivatives & analogs of Natural Compounds

详细说明

MP Biomedicals - 02194695

Cell Culture Reagent
Free Acid
Purity: 95-99%

MP Biomedicals - 02155239

(trans-9,trans-12-Octadecadienoic acid) Purity: 99% Sealed ampule(liquid). 1 ml = approx. 0.89 g

MP Biomedicals - 02100805

Free Acid
Purity: 95-99%

MP Biomedicals - 02102187

Free Acid
Purity: ~65%
1 ml = approx. 0.90 g

Sigma Aldrich - L1626

Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - L1268

Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - L1376

包装
1, 5, 10, 25 g in ampule
500 mg in ampule
10 mg in autosmp vl
密封安瓿瓶装。
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - L1012

Application
Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.
包装
Sealed ampule.
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - W338001

包装
1 kg in glass bottle
1 sample in glass bottle
25, 100 g in glass bottle
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - 233927

Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - 62240

Caution
0-4°C 储存时部分结晶
包装
1 L in glass bottle
250 mL in glass bottle
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - 62230

Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.

Sigma Aldrich - 62235

Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes 1.