(4-aminobutyl)(3-aminopropyl)amine trihydrochloride

• ChemBase编号: 102175
• 分子式: C7H22Cl3N3
• 平均质量: 254.62868
• 单一同位素质量: 253.08793076
• SMILES: Cl.Cl.Cl.NCCCCNCCCN
• Canonical SMILES: NCCCNCCCCN.Cl.Cl.Cl
• InChI: InChI=1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• InChIKey: LCNBIHVSOPXFMR-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: (4-aminobutyl)(3-aminopropyl)amine trihydrochloride
• IUPAC传统名: spermidine trihydrochloride
• 别名: 亚精胺 三盐酸盐; Spermidine trihydrochloride; N1-(3-Aminopropyl)butane-1,4-diamine trihydrochloride; N-(3-Aminopropyl)-1,4-Butanediamine trihydrochloride; SPERMIDINE TRIHYDROCHLORIDE

登记号

• CAS号: 334-50-9
• EC号: 206-379-0
• MDL号: MFCD00012918
• Beilstein号: 3552356
• PubChem SID: 24277993; 162089581; 24888218
• PubChem CID: 9539

理论计算性质

• 质子受体: 3
• 质子供体: 3
• LogD (pH = 5.5): -10.062785
• LogD (pH = 7.4): -7.799325
• Log P: -1.1495639
• 摩尔折射率: 44.9684 cm^3
• 极化性: 18.22489 Å^3
• 极化表面积: 64.07 Å^2
• 可自由旋转的化学键: 7
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble1 M at 20 °C, clear, colorless
• 熔点: 250-263°C; 257-259 °C(lit.)
• 紫外吸收波长: λ: 260 nm Amax: 0.2; λ: 280 nm Amax: 0.1
• pH值: 3.0-6.0 (25 °C, 1 M in H2O)

安全信息

• 保存条件: 0°C, Desiccate
• RTECS编号: EJ7023000
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 联合国危险货物编号: 1759
• 德国WGK号: 3
• 联合国危险货物等级: 8
• 联合国危险货物包装类别(PG): II
• 澳大利亚Hazchem: 2X
• 危险公开号: 36/37/38; R:36/37/38
• 安全公开号: 26-36; S:20-25-26-37/39
• 欧盟危险货物分类: C10
• 欧盟危险识别号(EUHIN): 8B
• 美国ERG指导号: 154
• GHS危险品标识: GHS07
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• GHS警示性声明: P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 保存温度: 2-8°C; room temp

药理学性质

• 相关基因信息: human ... NOS1(4842)

产品相关信息

• 纯度: ≥98% (TLC); ≥99.5% (AT); 95+%; 99%
• 杂质: insoluble matter, passes filter test
• 痕量阳离子: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• 痕量阴离子: sulfate (SO42-): ≤50 mg/kg
• λ: 1 M in H2O
• 产品线: BioXtra
• 线性分子式: NH2(CH2)3NH(CH2)4NH2 · 3HCl

详细说明

MP Biomedicals - 02100472

Crystalline Purity: 99%
Forms stable compounds with nucleic acids.

Sigma Aldrich - S125

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - S2501

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
包装
1, 5, 25 g in poly bottle
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - 85578

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Other Notes
Buffer component for chromosome isolation in bivariate flow cytogenetic analysis and sorting1.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - 233994

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
包装
5 g in glass bottle
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.